BioAssay by Target (List) for Gene (Select 2321) - PubChem BioAssay - NCBI

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Select item 19634541.

Mobility-Shift Assay from US Patent US11912663: "Multi-targeted tyrosine kinase inhibitors and their pharmaceutical uses"

Source:: BindingDB

Protein Targets:: Fibroblast growth factor receptor 2; ...
Total:: 5

Assay data:14 Active, 15 Activity ≤ 1 µM, 15 Tested

AID:: 1963454

Summary Related BioAssays by Target

Select item 19629382.

FLT1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Tested

AID:: 1962938

Summary Related BioAssays by Target

Select item 19628343.

FLT1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Tested

AID:: 1962834

Summary Related BioAssays by Target

Select item 19627184.

FLT1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Tested

AID:: 1962718

Summary Related BioAssays by Target

Select item 19626195.

FLT1 SGC Tm panel (DSF)

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Tested

AID:: 1962619

Summary Related BioAssays by Target

Select item 19608476.

Inhibition of VEGFR1 (unknown origin) at 10 uM by biochemical hotspot kinase assay relative to control

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Tested

AID:: 1960847

Summary Related BioAssays by Target

Select item 19559457.

Inhibition of FLT1 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Tested

AID:: 1955945

Summary Related BioAssays by Target

Select item 19497838.

Inhibition of VEGFR1 (unknown origin) in presence of ATP

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1949783

Summary Related BioAssays by Target

Select item 19488909.

Inhibition of human recombinant GST-fused VEGFR1 kinase domain transphosphorylation expressed in baculovirus expression system using poly-Glu-Tyr (4:1) as substrate measured after 10 mins in presence of gamma-[33P]-ATP by scintillation counting analysis

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:9 Active, 8 Activity ≤ 1 µM, 9 Tested

AID:: 1948890

Summary Related BioAssays by Target

Select item 194863210.

Binding affinity to recombinant FLT1 (unknown origin) assessed as dissociation constant by DSF assay

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1948632

Summary Related BioAssays by Target

Select item 194862111.

Inhibition of recombinant FLT1 (unknown origin) at 10 uM by DSF assay relative to staurosporine

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Tested

AID:: 1948621

Summary Related BioAssays by Target

Select item 194861012.

Binding affinity to recombinant FLT1 (unknown origin) assessed as change in melting temperature at 10 uM by DSF assay

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Tested

AID:: 1948610

Summary Related BioAssays by Target

Select item 194735813.

Inhibition of VEGFR1 (unknown origin) at 1 uM using Poly (Glu,Tyr) 4:1 as substrate incubated for 60 mins in presence of ATP by ELISA analysis relative to control

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Tested

AID:: 1947358

Summary Related BioAssays by Target

Select item 193793214.

Inhibition of VEGFR1 (unknown origin) in the presence of ATP at Km concentration

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1937932

Summary Related BioAssays by Target

Select item 193792215.

Inhibition of VEGFR1 (unknown origin)

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1937922

Summary Related BioAssays by Target

Select item 193789916.

Inhibition of recombinant VEGFR1 (unknown origin) in the presence of [p33]-ATP

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1937899

Summary Related BioAssays by Target

Select item 193789117.

Inhibition of recombinant VEGFR1 (unknown origin) incubated for 60 mins by ELISA analysis

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1937891

Summary Related BioAssays by Target

Select item 191945518.

Enzyme-linked immunosorbent assay (ELISA) from US Patent US11655239: "Fused ring pyrimidine amino compound and preparation method, pharmaceutical composition, and use thereof"

Source:: BindingDB

Protein Targets:: ALK tyrosine kinase receptor; ...
Total:: 23

Assay data:32 Active, 18 Activity ≤ 1 nM, 32 Activity ≤ 1 µM, 32 Tested

AID:: 1919455

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191464619.

Selectivity interaction (Enzyme panel (CEREP screen)) EUB0000749a FLT1

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Tested

AID:: 1914646

Summary Related BioAssays by Target

Select item 191375320.

Selectivity interaction (Kinase panel (activity or binding assay)) EUB0000674a FLT1

Source:: ChEMBL

Protein Target:: Vascular endothelial growth factor receptor 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913753

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

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BioAssays with protein sequences specified as targets
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BioAssays with gene sequences specified as RNAi targets and the activity is active

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BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (16)
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Activity (IC50, etc) ≤ 1 µM (241)
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BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
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Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
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BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

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BioAssays extracted from the literature
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BioAssays deposited by the NIH Molecular Libraries Program
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BioAssay by Target (List) for Gene (Select 2321) (760)
PubChem BioAssay
Gene Links for GEO Profiles (Select 65664695) (1)
Gene
KMT2C lysine methyltransferase 2C [Homo sapiens]
KMT2C lysine methyltransferase 2C [Homo sapiens]
Gene ID:58508

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