BioAssay by Target (List) for Gene (Select 2041) - PubChem BioAssay - NCBI

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Select item 19583631.

Inhibition of EphA1 (unknown origin) at 1 uM relative to control

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:3 Tested

AID:: 1958363

Summary PubMed Citation Related BioAssays by Target

Select item 19144572.

Selectivity interaction (KinomeScan (DiscoverX)) EUB0000289c EPHA1

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Tested

AID:: 1914457

Summary Related BioAssays by Target

Select item 19144563.

Selectivity interaction (KinomeScan (DiscoverX, competition-binding assay)) EUB0000289c EPHA1

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Tested

AID:: 1914456

Summary Related BioAssays by Target

Select item 19134284.

Selectivity interaction (NanoBRET assay (HEK293T cells)) EUB0000143b EPHA1

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913428

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 18628745.

Inhibition of EphA1 (unknown origin)

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1862874

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18354506.

EPHA1 DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Tested

AID:: 1835450

Summary Related BioAssays by Target

Select item 18349507.

EphA1(h) Kinase panel

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Tested

AID:: 1834950

Summary Related BioAssays by Target

Select item 18347568.

EphA1(h) Millipore kinase panel

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Tested

AID:: 1834756

Summary Related BioAssays by Target

Select item 18341149.

Inhibition of EPHA1 (unknown origin) at 1 uM

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Tested

AID:: 1834114

Summary PubMed Citation Related BioAssays by Target

Select item 182301910.

Inhibition of human recombinant EPHA1 incubated for 1 hrs by HTRF KinEASE TK assay

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1823019

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 180308811.

Mobility Shift Assay from US Patent US9365572: "PI3K and/or mTOR inhibitor"

Source:: BindingDB

Protein Targets:: 3-phosphoinositide-dependent protein kinase 1; ...
Total:: 51

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1803088

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 179406612.

KinomeScan assay: inhibition of EPHA1

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:108 Tested

AID:: 1794066

Summary Related BioAssays by Target

Select item 179365913.

EphA1(EPA1LGY1) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793659

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179336814.

EphA1(EPA1LGY1) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793368

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179307415.

EphA1(EPA1LGY1) Takeda global kinase panel

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1793074

Summary Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 179266016.

EphA1(h) Eurofins kinase panel

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Tested

AID:: 1792660

Summary Related BioAssays by Target

Select item 179227217.

EPHA1 ProQinase selectivity panel

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Tested

AID:: 1792272

Summary Related BioAssays by Target

Select item 179158818.

EPHA1 Kinase activity screen

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Tested

AID:: 1791588

Summary Related BioAssays by Target

Select item 179099019.

EPHA1 Kinase screen

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Tested

AID:: 1790990

Summary Related BioAssays by Target

Select item 179016920.

EPHA1 Invitrogen selectivity data (BI)

Source:: ChEMBL

Protein Target:: Ephrin type-A receptor 1

Assay data:1 Tested

AID:: 1790169

Summary Related BioAssays by Target

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Target

Proteins (3)
BioAssays with protein sequences specified as targets
RNAi Target, Active (9)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (30)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (25)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (34)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (40)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (187)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (45)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (155)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (74)
BioAssays deposited by other experimentalists

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