BioAssay by Target (List) for Gene (Select 1990) - PubChem BioAssay - NCBI

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Select item 6518111.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:9227 Active, 64752 Tested

AID:: 651811

Summary PubMed Citation

Select item 19042.

siRNA Circadian Assay

Source:: The Genomics Institute of the Novartis Research Foundation (GNF)

Assay data:527 Active, 33364 Tested

AID:: 1904

Summary PubMed Citation Related BioAssays by Depositor

Select item 664663.

Binding affinity against human Elastase

Source:: ChEMBL

Protein Target:: Chymotrypsin-like elastase family member 1

Assay data:11 Active, 2 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 15 Tested

AID:: 66466

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 3321794.

Inhibition of Flavobacterium meningosepticum PEP at 12.2 uM relative to control

Source:: ChEMBL

Protein Target:: Chymotrypsin-like elastase family member 1

Assay data:1 Tested

AID:: 332179

Summary PubMed Citation Related BioAssays by Target

Select item 3321805.

Inhibition of Flavobacterium meningosepticum PEP at 97.6 uM relative to control

Source:: ChEMBL

Protein Target:: Chymotrypsin-like elastase family member 1

Assay data:1 Tested

AID:: 332180

Summary PubMed Citation Related BioAssays by Target

Select item 3321906.

Inhibition of Flavobacterium meningosepticum PEP

Source:: ChEMBL

Protein Target:: Chymotrypsin-like elastase family member 1

Assay data:5 Active, 2 Activity ≤ 1 µM, 5 Tested

AID:: 332190

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 3322537.

Inhibition of Flavobacterium meningosepticum PEP at 2.4 uM relative to control

Source:: ChEMBL

Protein Target:: Chymotrypsin-like elastase family member 1

Assay data:1 Tested

AID:: 332253

Summary PubMed Citation Related BioAssays by Target

Select item 4637318.

Inhibition of elastase after 20 mins

Source:: ChEMBL

Protein Target:: Chymotrypsin-like elastase family member 1

Assay data:9 Tested

AID:: 463731

Summary PubMed Citation Related BioAssays by Target

Select item 4692359.

Inhibition of elastase

Source:: ChEMBL

Protein Target:: Chymotrypsin-like elastase family member 1

Assay data:1 Tested

AID:: 469235

Summary PubMed Citation Related BioAssays by Target

Select item 50816010.

Inhibition of human Pancreatic elastase 1

Source:: ChEMBL

Protein Target:: Chymotrypsin-like elastase family member 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 508160

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 62409911.

An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Assay data:497 Active, 21019 Tested

AID:: 624099

Summary PubMed Citation

Select item 65181012.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:826 Active, 18119 Tested

AID:: 651810

Summary PubMed Citation

Select item 191446313.

Selectivity interaction (Serine protease panel) EUB0000735a CELA1

Source:: ChEMBL

Protein Target:: Chymotrypsin-like elastase family member 1

Assay data:1 Tested

AID:: 1914463

Summary Related BioAssays by Target

Select item 74312114.

Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:167 Active, 26449 Tested

AID:: 743121

Select item 74345415.

RNAi screen for vorinostat resistance genes - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:450 Active, 18118 Tested

AID:: 743454

Summary PubMed Citation

Select item 111728116.

A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:555 Active, 64752 Tested

AID:: 1117281

Summary PubMed Citation

Select item 111735717.

InfectX: Pathogen infection siRNA screens

Source:: InfectX Consortium

Assay data:115372 Tested

AID:: 1117357

Summary PubMed Citation

Select item 115950618.

Identification of proteins required for the processing of the EWS-FLI1 nascent transcript

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:59220 Tested

AID:: 1159506

Select item 115957819.

A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:1034 Active, 18120 Tested

AID:: 1159578

Summary Related BioAssays by Depositor

Select item 115958420.

A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:2442 Active, 18052 Tested

AID:: 1159584

Summary PubMed Citation

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Target

Proteins (1)
BioAssays with protein sequences specified as targets
RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (4)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (3)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (5)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (10)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (9)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (13)
BioAssays deposited by other experimentalists

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