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Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counting
Assay data:4 Active, 11 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Effective concentration which increases intracellular c-AMP production in mouse Prostanoid EP4 receptor
Assay data:19 Active, 18 Activity ≤ 1 µM, 19 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Effective concentration for increased intracellular c-AMP production by mouse Prostanoid EP4 receptor
Assay data:13 Active, 13 Activity ≤ 1 µM, 13 Tested
Binding affinity towards mouse Prostanoid EP4 receptor in CHO cells.
Assay data:3 Active, 2 Activity ≤ 1 µM, 17 Tested
Evaluated for its competitive binding affinity towards mouse Prostanoid EP4 receptor in CHO cells expressing prostanoid receptor
Assay data:20 Active, 3 Activity ≤ 1 nM, 20 Activity ≤ 1 µM, 20 Tested
Affinity for mouse Prostanoid EP4 receptor expressed in CHO cells
Assay data:13 Active, 4 Activity ≤ 1 nM, 13 Activity ≤ 1 µM, 13 Tested
Binding affinity for mouse Prostanoid EP4 receptor
Assay data:4 Active, 13 Tested
Ability to inhibit the binding of [3H]PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP4
Assay data:5 Active, 14 Tested
Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cells by liquid scintillation counting
Assay data:13 Active, 2 Activity ≤ 1 µM, 19 Tested
Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cell membrane
Assay data:6 Active, 5 Activity ≤ 1 µM, 6 Tested
Displacement of [3H]PGE3 from mouse EP4 receptor expressed in CHO cells by liquid scintillation counting
Assay data:6 Active, 3 Activity ≤ 1 µM, 7 Tested
Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counter
Assay data:7 Active, 1 Activity ≤ 1 µM, 10 Tested
Displacement of [3H]PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counting
Assay data:23 Active, 22 Activity ≤ 1 µM, 23 Tested
Binding affinity to mouse EP4 receptor by competitive binding assay
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Agonist activity at mouse EP4 receptor expressed in CHO cells assessed as cAMP production
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Antagonist activity at mouse EP4 receptor transfected in CHO/Galpha16 cells preincubated for 15 mins followed by PGE2 addition by calcium flux assay
Assay data:8 Active, 8 Activity ≤ 1 µM, 10 Tested
Displacement of [3H]PGE2 from mouse prostaglandin EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counting
Assay data:2 Active, 2 Activity ≤ 1 µM, 11 Tested
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter
Assay data:27 Active, 10 Activity ≤ 1 nM, 27 Activity ≤ 1 µM, 27 Tested
Assay data:16 Active, 5 Activity ≤ 1 nM, 16 Activity ≤ 1 µM, 16 Tested
Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by scintillation counting
Assay data:22 Active, 9 Activity ≤ 1 nM, 21 Activity ≤ 1 µM, 22 Tested
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