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Inhibition of MKP3 (unknown origin)
Assay data:3 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of His-tagged MKP3 (unknown origin) expressed in Escherichia coli BL21 cells using para-nitrophenyl phosphate as substrate incubated for 5 to 10 mins by microplate reader based spectrophotometric analysis
Assay data:9 Tested
Inhibition of MKP3 (unknown origin) expressed in Escherichia coli BL21 using p-nitrophenyl phosphate as substrate measured after 30 mins by UV-vis spectrophotometric method
Inhibition of recombinant His-tagged Dusp6 (unknown origin) assessed as reduction in ERK2-stimulated Dusp6 dephosphorylation of OMFP substrate at 100 uM using OMFP substrate and using ERK2 to Dusp6 at 10:1 ratio level by fluorescence based assay relative to control
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of recombinant His-tagged Dusp6 (unknown origin) assessed as reduction in basal Dusp6 activity at 100 uM using OMFP substrate by fluorescence based assay
Inhibition of recombinant His-tagged Dusp6 (unknown origin) assessed as reduction in ERK2-stimulated Dusp6 dephosphorylation of OMFP substrate at 100 uM using OMFP substrate by fluorescence based assay relative to control
Inhibition of recombinant His-tagged Dusp6 (unknown origin) assessed as suppression of pBRK2 dephosphorylation at 1 mM incubated for 60 mins by immunoblotting
Assay data:1 Active, 1 Tested
Inhibition of recombinant His-tagged Dusp6 (unknown origin) assessed as suppression of pBRK2 dephosphorylation at 100 uM incubated for 60 mins by immunoblotting
Assay data:1 Active, 2 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Inhibition of Myc-tagged human Dusp6 expressed in TPA-stimulated human HeLa cells assessed as suppression of Dusp6-induced reduction in ERK phosphorylation at 0.5 to 2 uM by immunostaining based assay
Inhibition of Myc-tagged human Dusp6 expressed in TPA-stimulated human HeLa cells assessed as suppression of Dusp6-induced reduction in ERK phosphorylation by immunostaining based assay
Inhibition of full length DUSP6 (unknown origin) assessed as reduction in de-phosphorylation of GST-tagged recombinant phosphorylated ERK2 incubated for 15 mins by SDS-PAGE based immunoblot assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Inhibition of MKP3 (unknown origin) expressed in Escherichia coli BL21(DE3) using DIFMUP as substrate preincubated for 20 mins followed by substrate addition measured after 20 mins by phosphatase assay
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Secondary screen TNF readout
Assay data:731 Active, 3462 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
Inhibition of recombinant MKP3 (unknown origin) using OMFP as substrate after 1 hr by fluorescence assay
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
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