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Antimycobacterial activity scale was evaluated and found to be inactive against human Dihydrofolate reductase
Assay data:8 Activity ≤ 1 µM, 8 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibitory activity against Leu22-Phe mutant human Dihydrofolate reductase
Assay data:16 Active, 3 Activity ≤ 1 nM, 16 Activity ≤ 1 µM, 16 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of recombinant Dihydrofolate reductase from humans.
Assay data:20 Active, 7 Activity ≤ 1 µM, 20 Tested
Inhibition of human dihydrofolate reductase (DHFR)
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of human dihydrofolate reductase (DHFR) enzyme
Assay data:10 Active, 9 Activity ≤ 1 µM, 10 Tested
Ability to inhibit recombinant human dihydrofolate reductase; Not available
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Antimycobacterial activity scale was evaluated and found to be active against human Dihydrofolate reductase; ND is No Data
Assay data:3 Tested
Assay data:1 Tested
Antimycobacterial activity scale against human Dihydrofolate reductase; ND is No Data
Assay data:12 Tested
Cytotoxicity by selective inhibition against human dihydrofolate reductase (DHFR); NI=no inhibition
Cytotoxicity by selective inhibition against human dihydrofolate reductase (DHFR);NA is no inhibition
Tested in vitro for relative activity against CCRF-CEM human Leukemic lymphoblast by using DHFR as primary target
<Antimycobacterial activity scale was evaluated and found to be inactive against human Dihydrofolate reductase
Assay data:1 Activity ≤ 1 µM, 1 Tested
Antimycobacterial activity scale found to be highly active against human dihydrofolate reductase.
Assay data:32 Active, 32 Activity ≤ 1 µM, 32 Tested
Antimycobacterial activity scale was evaluated and found to be highly active against human Dihydrofolate reductase ranges from 100-1000
Assay data:6 Activity ≤ 1 µM, 6 Tested
Inhibitory activity against recombinant human dihydrofolate reductase (DHFR)
Assay data:3 Active, 2 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Antimycobacterial activity scale was evaluated and found to be moderately active against human Dihydrofolate reductase
Assay data:2 Activity ≤ 1 µM, 2 Tested
Antimycobacterial activity scale was evaluated and found to be moderately active against human Dihydrofolate reductase Ranges from 100-1000
Antimycobacterial activity scale was evaluated and found to be moderately active against human Dihydrofolate reductase ranges from 100-1000
Antimycobacterial activity scale was evaluated and found to be moderately active against human Dihydrofolate reductase ranges from 100-1000.
Assay data:3 Activity ≤ 1 µM, 3 Tested
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