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Stabilization of GIRK2 channel in C57BL6 mouse brain DAergic neurons assessed as recovery of GABAB receptor stimulation-mediated firing inhibition treated with 100 uM dopamine and 10 uM sulpiride D2 antagonist under continuous perfusion followed by 300 nM baclofen treated at 300 uM measured after 15 mins by multi-electrode array (Rvb = 24.94 +-/ 14.46%)
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Stabilization of GIRK2 channel in C57BL6 mouse brain DAergic neurons assessed as recovery of D2 receptor stimulation-mediated firing inhibition in presence of 100 nM quinpirole under continuous perfusion followed by treated at 300 uM measured after 15 mins by multi-electrode array (Rvb = 4.07 +-/ 3.6%)
Mouse Kir3.2 (Inwardly rectifying potassium channels)
Assay data:14 Active, 14 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
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