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Late-stage results from the probe development effort to identify antagonists of OPRK1: LCMS-based biochemical cytochrome P450 inhibition assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Same ProjectRelated BioAssays by Target
CYP2C9 Assay
Assay data:18731 Active, 95868 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Target
qHTS Assay for Inhibitors and Substrates of Cytochrome P450 2C9
Assay data:1327 Active, 507 Activity ≤ 1 µM, 10320 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
HTS Assay for Activators of Cytochrome P450 2A9
Assay data:1368 Active, 95868 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Cytochrome panel assay with activity outcomes
Assay data:11082 Active, 17143 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
siRNA Circadian Assay
Assay data:527 Active, 33364 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
Counterscreen panel assay for S1P4 antagonists: Ricerca HitProfilingScreen + CYP450
Late-stage counterscreen panel assay for S1P4 agonists: Ricerca HitProfilingScreen + CYP450
Late-stage counterscreen panel assay for GPR7 antagonists: Ricerca HitProfilingScreen + CYP450
Late-stage counterscreen panel assay for S1P4 agonists: Ricerca HitProfilingScreen + CYP450: Set 2
Late-stage counterscreen panel assay for GPR7 antagonists: Ricerca HitProfilingScreen + CYP450: Set 2
Late-stage counterscreen panel assay for S1P3 agonists: Ricerca HitProfilingScreen + CYP450
An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes
Assay data:497 Active, 21019 Tested
SummaryPubMed Citation
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)
Assay data:826 Active, 18119 Tested
Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)
Assay data:9227 Active, 64752 Tested
qHTS for inhibitors of CYP2C9 against the NCATS DSHEA and TCM libraries
Assay data:352 Active, 10 Activity ≤ 1 µM, 964 Tested
Late-stage results from the probe development effort to identify antagonists of vasopressin receptor 1a (V1a-R): LCMS-based biochemical cytochrome P450 inhibition assay
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
Summary
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
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