BioAssay by Target (List) for Gene (Select 14800) - PubChem BioAssay - NCBI

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Links from Gene

Items: 11

Select item 12604781.

Inhibition of AMPA receptor in mouse cortical neurons assessed as effect on AMPA currents

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 4

Assay data:1 Tested

AID:: 1260478

Summary Related BioAssays by Target

Select item 12248282.

Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout

Source:: Iain Fraser

Assay data:762 Active, 16821 Tested

AID:: 1224828

Summary Related BioAssays by Same Project

Select item 12248263.

Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout

Source:: Iain Fraser

Assay data:1106 Active, 16821 Tested

AID:: 1224826

Summary Related BioAssays by Same Project

Select item 10532084.

A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:788 Active, 16789 Tested

AID:: 1053208

Summary PubMed Citation

Select item 2728555.

Antagonist activity against AMPA receptor assessed as inhibition of SAMPA-induced depolarization of mouse cortex

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 4

Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 272855

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 1130246.

In vivo anticonvulsant activity was measured as median effective dose required to prevent tonic phase of seizure in DBA/2 mice

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 4

Assay data:6 Active, 61 Tested

AID:: 113024

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 1130237.

In vivo anticonvulsant activity was measured as median effective dose required to prevent clonic phase of seizure in DBA/2 mice

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 4

Assay data:1 Active, 61 Tested

AID:: 113023

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 920508.

Compound was tested for binding affinity against Ionotropic glutamate receptor AMPA using [3H]AMPA as a radioligand.

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 4

Assay data:19 Active, 11 Activity ≤ 1 µM, 27 Tested

AID:: 92050

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 920499.

Antagonism at ionotropic glutamate receptor AMPA in mouse cortical wedge preparation

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 4

Assay data:1 Tested

AID:: 92049

Summary PubMed Citation Related BioAssays by Target

Select item 9204810.

Compound was tested for in vitro binding affinity against Ionotropic glutamate receptor AMPA using [3H]AMPA ligand

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 4

Assay data:6 Active, 5 Activity ≤ 1 µM, 8 Tested

AID:: 92048

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9204711.

Antagonism at ionotropic glutamate receptor AMPA in mouse cortical wedge preparation

Source:: ChEMBL

Protein Targets:: Glutamate receptor 1; ...
Total:: 4

Assay data:4 Active, 5 Tested

AID:: 92047

Summary Compounds, Active PubMed Citation Related BioAssays by Target

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BioActivity

Active Compounds (6)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (3)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (2)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (6)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (1)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (8)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (3)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (2)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (7)
BioAssays extracted from the literature
Other (4)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 14800) (11)
PubChem BioAssay
RefSeq Protein Links for Gene (Select 14800) (6)
Protein
14800[uid] AND (alive[prop]) (1)
Gene
Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) [Mus musculus]
Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) [Mus musculus]
Gene ID:14800

Gene
Mus musculus glutamate receptor, ionotropic, AMPA2 (alpha 2) (Gria2), transcript...
Mus musculus glutamate receptor, ionotropic, AMPA2 (alpha 2) (Gria2), transcript variant 6, non-coding RNA
gi|1832261062|ref|NR_152147.2|

Nucleotide

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