BioAssay by Target (List) for Gene (Select 1387) - PubChem BioAssay - NCBI

Warning: The NCBI web site requires JavaScript to function. more...

Links from Gene

Items: 1 to 20 of 446

<< First< Prev

Page of 23

Select item 19201811.

In Vitro Activity Against CBP from US Patent US20240016795: "BROMODOMAIN INHIBITORS FOR ANDROGEN RECEPTOR-DRIVEN CANCERS"

Source:: BindingDB

Protein Targets:: CREB-binding protein; ...
Total:: 2

Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1920181

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19185062.

Inhibition of CBP/p300 in human COLO 320HSR cells assessed as decrease in H3K9 acetylation at 0.3 to 1000 nM measured by western blot analysis

Source:: ChEMBL

Protein Targets:: CREB-binding protein; ...
Total:: 2

Assay data:1 Tested

AID:: 1918506

Summary PubMed Citation Related BioAssays by Target

Select item 19185053.

Inhibition of CBP/p300 in human COLO 320HSR cells assessed as decrease in H3K27 acetylation at 0.3 to 1000 nM measured by western blot analysis

Source:: ChEMBL

Protein Targets:: CREB-binding protein; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1918505

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19185044.

Inhibition of CBP/p300 in human COLO 320HSR cells assessed as decrease in H3K18 acetylation at 0.3 to 1000 nM measured by western blot analysis

Source:: ChEMBL

Protein Targets:: CREB-binding protein; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1918504

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19184985.

Inhibition of CBP (unknown origin) using Histone H3 substrate at 1 uM relative to control

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Tested

AID:: 1918498

Summary PubMed Citation Related BioAssays by Target

Select item 19184746.

Inhibition of CBP/p300 in human COLO 320HSR cells assessed as reduction of C-myc levels measured after 24 hrs by HTRF assay

Source:: ChEMBL

Protein Targets:: CREB-binding protein; ...
Total:: 2

Assay data:25 Active, 16 Activity ≤ 1 µM, 27 Tested

AID:: 1918474

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19148377.

Selectivity interaction (BROMOscan? panel (DiscoverX)) EUB0000247b CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914837

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 19147598.

Selectivity interaction (BROMOscan (DiscoverX)) EUB0000191c CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Tested

AID:: 1914759

Summary Related BioAssays by Target

Select item 19147449.

Selectivity interaction (Bromodomain panel (DSF assay)) EUB0000330a CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Tested

AID:: 1914744

Summary Related BioAssays by Target

Select item 191473710.

Selectivity interaction (Bromoscan (DiscoverX, BromoKdELECT)) EUB0000004c CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Tested

AID:: 1914737

Summary Related BioAssays by Target

Select item 191473611.

Selectivity interaction (BromoKdELECT (DiscoverX)) EUB0000004c CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Active, 1 Tested

AID:: 1914736

Summary Compounds, Active Related BioAssays by Target

Select item 191472412.

Selectivity interaction (DSF assay) EUB0000195c CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Tested

AID:: 1914724

Summary Related BioAssays by Target

Select item 191472313.

Selectivity interaction (Biolayer Interferometry experiment) EUB0000195c CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914723

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191472214.

Selectivity interaction (AlphaScreen) EUB0000195c CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1914722

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191326515.

Affinity Biochemical interaction (ITC) EUB0000208c CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913265

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191326316.

Affinity Biochemical interaction (ITC) EUB0000195c CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913263

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191326017.

Affinity Biochemical interaction (TR-FRET assay (BHC domains)) EUB0000328a CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1913260

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191325718.

Affinity Biochemical interaction (TR-FRET assay (BHC domains)) EUB0000326a CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Active, 1 Tested

AID:: 1913257

Summary Compounds, Active Related BioAssays by Target

Select item 191297719.

Affinity On-target Cellular interaction (NanoBRET assay (HEK293T cells)) EUB0000195c CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1912977

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191280320.

Affinity Phenotypic Cellular interaction (FRAP assay (displacement of the CBP bromodomain from chromatin)) EUB0000208c CREBBP

Source:: ChEMBL

Protein Target:: CREB-binding protein

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1912803

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

<< First< Prev

Page of 23

Supplemental Content

Filters: Manage Filters

Refine your results

• What's this?

Target

Proteins (5)
BioAssays with protein sequences specified as targets
RNAi Target, Active (8)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (241)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (9)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (133)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (212)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (38)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (398)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (48)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (7)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (363)
BioAssays extracted from the literature
NIH MLP (5)
BioAssays deposited by the NIH Molecular Libraries Program
Other (78)
BioAssays deposited by other experimentalists

Actions on your results

View or Download BioAssay in PubChem

Find related data

Recent activity

Clear Turn Off Turn On

BioAssay by Target (List) for Gene (Select 1387) (446)
PubChem BioAssay

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

You are here: NCBI > Chemicals & Bioassays > PubChem BioAssay