BioAssay by Target (List) for Gene (Select 12475) - PubChem BioAssay - NCBI

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Links from Gene

Items: 14

Select item 14479201.

Binding affinity to CD14/MD2 in Balb/c mouse splenocytes assessed as inhibition of LPS-induced TLR4-MyD88 pathway by measuring reduction in TNFalpha expression at 1 to 10 uM preincubated for 30 mins followed by LPS stimulation for 5 hrs by qRT-PCR method

Source:: ChEMBL

Protein Targets:: Lymphocyte antigen 96; ...
Total:: 3

Assay data:2 Active, 2 Tested

AID:: 1447920

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 14479192.

Binding affinity to CD14/MD2 in mouse RAW-Blue cells assessed as inhibition of LPS-induced TLR4 signaling preincubated for 30 mins followed by LPS stimulation measured after overnight incubation by secreted embryonic alkaline phosphatase reporter gene assay

Source:: ChEMBL

Protein Targets:: Lymphocyte antigen 96; ...
Total:: 3

Assay data:2 Tested

AID:: 1447919

Summary PubMed Citation Related BioAssays by Target

Select item 12248283.

Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout

Source:: Iain Fraser

Assay data:762 Active, 16821 Tested

AID:: 1224828

Summary Related BioAssays by Same Project

Select item 12248264.

Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout

Source:: Iain Fraser

Assay data:1106 Active, 16821 Tested

AID:: 1224826

Summary Related BioAssays by Same Project

Select item 11678925.

Activation of human TLR4/MD2 complex in mouse RAW264.7 cells assessed as induction of NFkappaB activation incubated for 18 hrs

Source:: ChEMBL

Protein Targets:: Lymphocyte antigen 96; ...
Total:: 3

Assay data:1 Active, 1 Tested

AID:: 1167892

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 11595996.

TLR-pathway-mouse_LPS ligand_TNF readout

Source:: Iain Fraser

Assay data:130 Active, 756 Tested

AID:: 1159599

Summary PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project

Select item 11595957.

TLR-pathway-mouse_P3C ligand_TNF readout

Source:: Iain Fraser

Assay data:115 Active, 756 Tested

AID:: 1159595

Summary PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project

Select item 11595938.

TLR-pathway-mouse_LPS ligand_NFkB readout

Source:: Iain Fraser

Assay data:137 Active, 756 Tested

AID:: 1159593

Summary PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project

Select item 11595929.

TLR-pathway-mouse_R848 ligand_NFkB readout

Source:: Iain Fraser

Assay data:147 Active, 756 Tested

AID:: 1159592

Summary PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project

Select item 115959110.

TLR-pathway-mouse_R848 ligand_TNF readout

Source:: Iain Fraser

Assay data:130 Active, 756 Tested

AID:: 1159591

Summary PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project

Select item 115959011.

TLR-pathway-mouse_P3C ligand_NFkB readout

Source:: Iain Fraser

Assay data:128 Active, 756 Tested

AID:: 1159590

Summary PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project

Select item 106647712.

Inhibition of CD14 in mouse RAW264.7 cells at 20 uM by Western blotting analysis

Source:: ChEMBL

Protein Target:: Monocyte differentiation antigen CD14

Assay data:1 Tested

AID:: 1066477

Summary PubMed Citation Related BioAssays by Target

Select item 105320813.

A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:788 Active, 16789 Tested

AID:: 1053208

Summary PubMed Citation

Select item 75035414.

Activation of mouse TLR4/MD-2/CD14 complex in C57BL/6 mouse BMDC cells assessed as NFkappaB activation by SEAP assay in presence of LPS-RS

Source:: ChEMBL

Protein Targets:: Lymphocyte antigen 96; ...
Total:: 3

Assay data:1 Tested

AID:: 750354

Summary PubMed Citation Related BioAssays by Target

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BioActivity

Active Compounds (2)
BioAssays with compounds reported as biologically active

Experiment Type

Summary (2)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Primary Screening (1)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (5)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (9)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (8)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (5)
BioAssays extracted from the literature
Other (9)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 12475) (14)
PubChem BioAssay
Carnation mottle virus isolate BC-1 ORF2, ORF1, ORF3, ORF4, and ORF5 genes, comp...
Carnation mottle virus isolate BC-1 ORF2, ORF1, ORF3, ORF4, and ORF5 genes, complete cds
gi|2329659948|gb|OK558667.1|

Nucleotide
Gene Links for GEO Profiles (Select 65172264) (1)
Gene
PICALM phosphatidylinositol binding clathrin assembly protein [Homo sapiens]
PICALM phosphatidylinositol binding clathrin assembly protein [Homo sapiens]
Gene ID:8301

Gene
FABP3P2 fatty acid binding protein 3 pseudogene 2 [Homo sapiens]
FABP3P2 fatty acid binding protein 3 pseudogene 2 [Homo sapiens]
Gene ID:56677

Gene

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