Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Purinergic P2Y Eurofins Panlabs panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Purinergic P2Y Eurofins-Panlabs radioligand binding assay
Assay data:4 Tested
Assay data:9 Tested
Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced inositol-1-phosphate accumulation preincubated for 30 mins followed by UDP addition and measured after 30 mins by liquid scintillation counting method
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium influx preincubated for 20 mins followed by UDP addition measured at 0.4 secs interval for 60 times by Oregon Green BAPTA-1/AM dye-based fluorescence assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium influx at 10 to 100 uM preincubated for 20 mins followed by UDP addition measured at 0.4 secs interval for 60 times by Oregon Green BAPTA-1/AM dye-based fluorescence assay
Assay data:35 Tested
SummaryPubMed CitationRelated BioAssays by Target
Rat P2Y6 receptor (P2Y receptors)
Assay data:2 Active, 2 Tested
Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration at 100 uM by spectrofluorimetry
Agonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by spectrofluorimetry
Assay data:5 Active, 3 Activity ≤ 1 µM, 8 Tested
Antagonist activity at rat P2Y purinoceptor 6 expressed in human 1321N1 cells assessed as inhibition of UDP-induced increase in intracellular calcium concentration by spectrofluorimetry
Assay data:8 Tested
Antagonist activity at rat P2Y6 receptor expressed in astrocytoma cells assessed as inhibition of intracellular calcium mobilization
Assay data:3 Active, 6 Tested
Agonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as calcium elevation by fura2/AM assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced increase in intracellular calcium concentration by dual-excitation spectrofluorimetric analysis
Assay data:3 Tested
Agonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration at 100 uM by dual-excitation spectrofluorimetric analysis
Assay data:3 Active, 3 Tested
Agonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitation spectrofluorimetric analysis
Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced receptor activation at 100 uM relative to UDP
Assay data:6 Tested
Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization by NOVOstar plate reader
Antagonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as inhibition of UDP-induced intracellular calcium mobilization at 100 uM by NOVOstar plate reader
Assay data:13 Tested
Effect on P2Y6 receptor-mediated cell motility in Wistar rat microglia at 100 uM by chemotaxis assay
Assay data:1 Active, 2 Tested
Effect on P2Y6 receptor-mediated cell motility in Wistar rat microglia assessed as formation of lamellipodia-like membrane ruffles at 10 uM after 5 mins
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on