BioAssay by Target (List) for Gene (Select 116444) - PubChem BioAssay - NCBI

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Select item 19600061.

Antagonist activity at NMDA receptor (unknown origin) assessed as inhibition constant

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1960006

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19508042.

Displacement of [3H]ifenprodyl from NMDA receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:2 Tested

AID:: 1950804

Summary PubMed Citation Related BioAssays by Target

Select item 19413413.

Displacement of [3H]MDL from NMDA receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1941341

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 19257704.

Inhibition of NMDA receptor (unknown origin) at 10 uM

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:1 Tested

AID:: 1925770

Summary PubMed Citation Related BioAssays by Target

Select item 19155065.

Binding affinity to TCP-stimulated NMDA (unknown origin)

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:1 Active, 1 Tested

AID:: 1915506

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 19154966.

Binding affinity to NMDA receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested

AID:: 1915496

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18958367.

Binding affinity to NMDAR (unknown origin) assessed as inhibition constant by [3H]MK-801 binding assay

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1895836

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18776508.

Inhibition of NMDA receptor (unknown origin) at 50 uM by radioligand receptor binding assay relative to control

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:1 Tested

AID:: 1877650

Summary PubMed Citation Related BioAssays by Target

Select item 18729439.

Inhibition of NMDA receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1872943

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 186403510.

Binding affinity to NMDA receptor (unknown origin) at 100 uM patch clamp assay

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:1 Tested

AID:: 1864035

Summary PubMed Citation Related BioAssays by Target

Select item 185914311.

Binding affinity to NMDA receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:10 Tested

AID:: 1859143

Summary PubMed Citation Related BioAssays by Target

Select item 185913412.

Antagonist activity at NMDA receptor (unknown origin) assessed as NMDA-induced depolarizations

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:4 Tested

AID:: 1859134

Summary PubMed Citation Related BioAssays by Target

Select item 185913213.

Displacement of [3H]MK-801 from NMDA receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:2 Active, 2 Activity ≤ 1 µM, 5 Tested

AID:: 1859132

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 185912114.

Displacement of [3H]NMDA from NMDA receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1859121

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 185912015.

Displacement of [3H]L-689560 from NMDA receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested

AID:: 1859120

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 185911916.

Displacement of [3H]MDL from NMDA receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested

AID:: 1859119

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 185911817.

Displacement of [3H]AMPA from NMDA receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:4 Active, 5 Tested

AID:: 1859118

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 185911718.

Displacement of [3H]kainic acid from NMDA receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:2 Tested

AID:: 1859117

Summary PubMed Citation Related BioAssays by Target

Select item 185911619.

Displacement of [3H]CGP-39653 from NMDA receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:2 Tested

AID:: 1859116

Summary PubMed Citation Related BioAssays by Target

Select item 185911520.

Displacement of [3H]DCKA from NMDA receptor (unknown origin) at 10 ng/ml relative to control

Source:: ChEMBL

Protein Targets:: Glutamate receptor ionotropic, NMDA 1; ...
Total:: 7

Assay data:2 Tested

AID:: 1859115

Summary PubMed Citation Related BioAssays by Target

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Target

RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (64)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (3)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (48)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (94)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (166)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (161)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (17)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 116444) (179)
PubChem BioAssay
IucA/IucC family siderophore biosynthesis protein, partial [Acinetobacter bauman...
IucA/IucC family siderophore biosynthesis protein, partial [Acinetobacter baumannii]
gi|2639501948|ref|WP_322842968.1|

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