BioAssay by Target (List) for Gene (Select 11330) - PubChem BioAssay - NCBI

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Select item 2005361.

Evaluated for percent inhibition of human Serine protease chymotrypsin at 20 ug/mL; NA means not active

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:1 Tested

AID:: 200536

Summary PubMed Citation Related BioAssays by Target

Select item 526332.

Initial rate of reaction between chymotrypsin and BzArg p-nitro-anilide in the presence of 400 uM at pH 5

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:1 Tested

AID:: 52633

Summary PubMed Citation Related BioAssays by Target

Select item 526343.

Initial rate of reaction between chymotrypsin and BzArg p-nitro-anilide in the presence of 400 uM at pH 7

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:2 Tested

AID:: 52634

Summary PubMed Citation Related BioAssays by Target

Select item 527804.

Inhibitory activity against chymotrypsinogen

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:6 Active, 34 Tested

AID:: 52780

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 527905.

Inhibition of chymotrypsin at 250 uM

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:42 Tested

AID:: 52790

Summary PubMed Citation Related BioAssays by Target

Select item 2003926.

Compound was evaluated for inhibition of Serine protease chymotrypsin at 1.3 uM

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:1 Tested

AID:: 200392

Summary PubMed Citation Related BioAssays by Target

Select item 2003937.

Compound was evaluated for inhibition of Serine protease chymotrypsin at 1.7 uM

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:1 Tested

AID:: 200393

Summary PubMed Citation Related BioAssays by Target

Select item 2003948.

Compound was evaluated for inhibition of Serine protease chymotrypsin at 15 uM

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:1 Tested

AID:: 200394

Summary PubMed Citation Related BioAssays by Target

Select item 2003959.

Compound was evaluated for inhibition of Serine protease chymotrypsin at 1 uM

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:1 Tested

AID:: 200395

Summary PubMed Citation Related BioAssays by Target

Select item 20053010.

Compound was evaluated for inhibition of Serine protease chymotrypsin

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:2 Active, 4 Tested

AID:: 200530

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 20053111.

Compound was evaluated for the inhibitory constant against human Serine protease chymotrypsin

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:2 Tested

AID:: 200531

Summary PubMed Citation Related BioAssays by Target

Select item 20053212.

Compound was tested in vitro for its ability to inhibit serine protease chymotrypsin using suc-Ala-Ala-Pro-Phe-p-nitroanilide as substrate

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:6 Tested

AID:: 200532

Summary PubMed Citation Related BioAssays by Target

Select item 20053313.

Inhibitory concentration against Human pancreatic Serine protease chymotrypsin

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:11 Active, 8 Activity ≤ 1 µM, 13 Tested

AID:: 200533

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 20053414.

Inhibitory concentration against Human pancreatic Serine protease chymotrypsin.

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:12 Tested

AID:: 200534

Summary PubMed Citation Related BioAssays by Target

Select item 20053515.

Inhibition of human Serine protease chymotrypsin at 20 ug/mL

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:14 Tested

AID:: 200535

Summary PubMed Citation Related BioAssays by Target

Select item 5263216.

Inhibition of chymotrypsin-catalyzed hydrolysis of BzArg p-nitroanilide by compound at pH 7.8

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:1 Tested

AID:: 52632

Summary PubMed Citation Related BioAssays by Target

Select item 20053717.

Compound was tested for inhibition of Serine protease chymotrypsin

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 200537

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 20053818.

Inhibitory activity against Serine protease chymotrypsin

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:6 Tested

AID:: 200538

Summary PubMed Citation Related BioAssays by Target

Select item 20053919.

Compound was evaluated for its inhibitory activity against Serine protease chymotrypsin

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:3 Active, 5 Tested

AID:: 200539

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 20054020.

Inhibitory activity against Serine protease chymotrypsin

Source:: ChEMBL

Protein Target:: Chymotrypsin-C

Assay data:1 Tested

AID:: 200540

Summary PubMed Citation Related BioAssays by Target

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Target

Proteins (1)
BioAssays with protein sequences specified as targets
RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (33)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (3)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (23)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (51)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (102)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (98)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (16)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 11330) (115)
PubChem BioAssay
Related DataSets for GEO Profiles (Select 114384885) (1)
GEO DataSets
Transforming growth factor beta effect on cytokine-activated, NOD-derived, splen...
Transforming growth factor beta effect on cytokine-activated, NOD-derived, splenic natural killer cells
Accession: GDS4948

GEO DataSets
11330[uid] AND (alive[prop]) (1)
Gene
CTRC chymotrypsin C [Homo sapiens]
CTRC chymotrypsin C [Homo sapiens]
Gene ID:11330

Gene

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