BioAssay by Target (List) for Gene (Select 1062) - PubChem BioAssay - NCBI

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Select item 6067411.

Inhibition of CENP-E ATPase activity at 20 uM

Source:: ChEMBL

Protein Target:: Centromere-associated protein E

Assay data:3 Tested

AID:: 606741

Summary PubMed Citation Related BioAssays by Target

Select item 7431212.

Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:167 Active, 26449 Tested

AID:: 743121

Select item 7274283.

Inhibition of CENP-E (unknown origin)-mediated ATP hydrolysis assessed as residual activity at 1 uM after 10 to 20 mins by spectrophotometric analysis

Source:: ChEMBL

Protein Target:: Centromere-associated protein E

Assay data:8 Tested

AID:: 727428

Summary PubMed Citation Related BioAssays by Target

Select item 7272834.

Inhibition of CENP-E (unknown origin)-mediated ATP hydrolysis assessed as residual activity at 10 uM after 10 to 20 mins by spectrophotometric analysis

Source:: ChEMBL

Protein Target:: Centromere-associated protein E

Assay data:1 Tested

AID:: 727283

Summary PubMed Citation Related BioAssays by Target

Select item 6594295.

Inhibition of MT-stimulated CENP-E ATPase activity

Source:: ChEMBL

Protein Target:: Centromere-associated protein E

Assay data:1 Tested

AID:: 659429

Summary PubMed Citation Related BioAssays by Target

Select item 6594286.

Inhibition of CENP-E ATPase activity

Source:: ChEMBL

Protein Target:: Centromere-associated protein E

Assay data:1 Tested

AID:: 659428

Summary PubMed Citation Related BioAssays by Target

Select item 6518117.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Ambion Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:9227 Active, 64752 Tested

AID:: 651811

Summary PubMed Citation

Select item 6518108.

Genome-wide high-content siRNA screens for regulators of Parkin translocation in selective mitophagy (Dharmacon Library)

Source:: National Center for Advancing Translational Sciences (NCATS)

Assay data:826 Active, 18119 Tested

AID:: 651810

Summary PubMed Citation

Select item 6240999.

An siRNA screen for human genes that are involved in human papilloma virus (HPV) E2 transcriptional repression of the E6 and E7 oncogenes

Source:: ICCB-Longwood Screening Facility, Harvard Medical School

Assay data:497 Active, 21019 Tested

AID:: 624099

Summary PubMed Citation

Select item 61434710.

Inhibition of CENP-E

Source:: ChEMBL

Protein Target:: Centromere-associated protein E

Assay data:2 Tested

AID:: 614347

Summary PubMed Citation Related BioAssays by Target

Select item 74345411.

RNAi screen for vorinostat resistance genes - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:450 Active, 18118 Tested

AID:: 743454

Summary PubMed Citation

Select item 50334712.

Inhibition of CENPE at 10 uM by puruvate kinsase-lactate dehydrogenase detection system

Source:: ChEMBL

Protein Target:: Centromere-associated protein E

Assay data:3 Tested

AID:: 503347

Summary PubMed Citation Related BioAssays by Target

Select item 49135313.

Inhibition of CENP-E ATPase activity at 20 uM

Source:: ChEMBL

Protein Target:: Centromere-associated protein E

Assay data:3 Tested

AID:: 491353

Summary PubMed Citation Related BioAssays by Target

Select item 46649814.

Inhibition of human CENPE at 10 uM

Source:: ChEMBL

Protein Target:: Centromere-associated protein E

Assay data:1 Tested

AID:: 466498

Summary PubMed Citation Related BioAssays by Target

Select item 46648615.

Inhibition of human CENPE at 1 uM

Source:: ChEMBL

Protein Target:: Centromere-associated protein E

Assay data:1 Tested

AID:: 466486

Summary PubMed Citation Related BioAssays by Target

Select item 39308316.

Inhibition of ATPase activity of CENPE by luminescent kinase assay

Source:: ChEMBL

Protein Target:: Centromere-associated protein E

Assay data:27 Tested

AID:: 393083

Summary PubMed Citation Related BioAssays by Target

Select item 33983417.

Inhibition of cloned human CENP-E

Source:: ChEMBL

Protein Target:: Centromere-associated protein E

Assay data:1 Tested

AID:: 339834

Summary PubMed Citation Related BioAssays by Target

Select item 29946318.

Inhibition of CENPE assessed as inhibition ATP hydrolysis by ATPase assay at 20 uM

Source:: ChEMBL

Protein Target:: Centromere-associated protein E

Assay data:4 Tested

AID:: 299463

Summary PubMed Citation Related BioAssays by Target

Select item 190419.

siRNA Circadian Assay

Source:: The Genomics Institute of the Novartis Research Foundation (GNF)

Assay data:527 Active, 33364 Tested

AID:: 1904

Summary PubMed Citation Related BioAssays by Depositor

Select item 162220.

RNAi Global Initiative pilot viability screen of human kinase and cell cycle genes

Source:: Dharmacon, a Horizon Discovery Group company

Assay data:5 Active, 840 Tested

AID:: 1622

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Target

RNAi Target, Active (7)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (4)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 µM (3)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (8)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (10)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (25)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (14)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (25)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (12)
BioAssays deposited by other experimentalists

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