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Inhibition of ERN2 (unknown origin) at 1 uM relative to control
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of ERN2 (unknown origin) at 1 uM
ERN2 Invitrogen Lab (UK) kinase screen (BI)
SummaryRelated BioAssays by Target
Inhibition of human ERN2 assessed as residual activity using MBP as substrate at 1 uM by [gamma-33P]-ATP assay relative to control
Inhibition of human ERN2 using MBP as substrate by [gamma-33P]-ATP assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human ERN2 using MBP as substrate assessed as residual activity at 1 uM by [gamma-33P]-ATP assay relative to control
Assay data:2 Tested
Inhibition of ERN2 (unknown origin) 1 uM relative to control
Inhibition of human ERN2 at 100 nM using MBP as substrate by [gamma-33P]-ATP assay
Inhibition of human ERN2 assessed as residual activity at 100 uM using MBP as substrate by [gamma-33P]-ATP assay relative to control
Inhibition of human ERN2 assessed as residual activity at 1 uM using MBP as substrate by [gamma-33P]-ATP assay relative to control
RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Inhibition of IRE2 in human SKCO1 cells at 1 uM after 4 hrs using biotin labeled DLKPGNILITGPDSQGLGR probe by mass-spectrometric analysis relative to control
Assay data:3 Tested
Kinobeads (epsilon), multiple immobilized ATP-competitive broad spectrum kinase inhibitors, used to assess residual binding of ~300 proteins simultaneously from cell lysate in the presence of a compound. Quantitative readout performed by mass spectrometry.
Assay data:5 Active, 4 Activity ≤ 1 µM, 240 Tested
Primary screen of kinases in signalling pathway between Protease activated receptor 2 (PAR2) and the ion channels Transient receptor potential vanilloid-4 (TRPV4) in HEK293 cells
Assay data:91 Active, 714 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SW620)
Assay data:15 Active, 794 Tested
SummaryPubMed CitationRelated BioAssays by Depositor
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (SNUC5)
Assay data:11 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HCT15)
Assay data:18 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (CAR1)
Assay data:9 Active, 794 Tested
A screen to identify synergistic combinations in colorectal cancer - Primary Screen (HT55)
Assay data:20 Active, 794 Tested
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