BioAssay by Target (List) for Gene (Select 10060) - PubChem BioAssay - NCBI

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Select item 939801.

Evaluated for K-ATP activity as stable twitch response through field-stimulated landrace pig detrusor assay (FSLPD)

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:1 Active, 1 Tested

AID:: 93980

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 800242.

Antiarrhythmic effect in Guinea pig papillary muscle KATP channel at 0.2 uM; ND=Not determined

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:1 Tested

AID:: 80024

Summary PubMed Citation Related BioAssays by Target

Select item 805903.

Potassium channel opening activity in guinea pig urinary bladder cells

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:1 Tested

AID:: 80590

Summary PubMed Citation Related BioAssays by Target

Select item 805914.

PEC50 for functional potassium channel opening activity in isolated bladder strips

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested

AID:: 80591

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 939745.

Evaluated for K-ATP activity in terms of change in membrane potential through guinea pig bladder assay

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:64 Active, 37 Activity ≤ 1 µM, 68 Tested

AID:: 93974

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 939756.

Evaluated for K-ATP activity in terms of membrane potential change, through guinea pig bladder assay

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:51 Active, 1 Activity ≤ 1 nM, 42 Activity ≤ 1 µM, 51 Tested

AID:: 93975

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 939767.

Evaluated for K-ATP activity as change in membrane potential in guinea pig bladder assay

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 93976

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 939778.

Evaluated for K-ATP activity in terms of stable twitch response through field-stimulated landrace pig detrusor assay

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:32 Active, 22 Activity ≤ 1 µM, 36 Tested

AID:: 93977

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 939789.

K-ATP activity in terms of stable twitch response through field-stimulated landrace pig detrusor assay

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:22 Active, 16 Activity ≤ 1 µM, 26 Tested

AID:: 93978

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9397910.

Evaluated for K-ATP activity as stable twitch response through field-stimulated landrace pig detrusor assay (FSLPD)

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 93979

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 8002311.

Antiarrhythmic effect in Guinea pig papillary muscle KATP channel at 2 uM

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:1 Tested

AID:: 80023

Summary PubMed Citation Related BioAssays by Target

Select item 9398112.

Evaluated for K-ATP activity in terms of stable twitch response through field-stimulated landrace pig detrusor assay

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:1 Active, 1 Activity ≤ 1 µM, 31 Tested

AID:: 93981

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9398213.

K-ATP activity in terms of stable twitch response through field-stimulated landrace pig detrusor assay

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:7 Active, 4 Activity ≤ 1 µM, 25 Tested

AID:: 93982

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9398314.

Evaluated for K-ATP activity as stable twitch response through field-stimulated landrace pig detrusor assay

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 93983

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9398415.

Evaluated for K-ATP activity as in vitro bladder relaxation in spontaneous Landrace pig detrusor strips (SLPD)

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested

AID:: 93984

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9398516.

Evaluated for K-ATP activity as in vitro bladder relaxation in spontaneous Landrace pig detrusor strips (SLPD)

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:4 Active, 4 Activity ≤ 1 µM, 4 Tested

AID:: 93985

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9532817.

In vitro ATP-sensitive potassium channel (KATP) activity in cells expressing human KATP channels Kir6.2 and sulfonylurea receptor 2B

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 9; ...
Total:: 2

Assay data:16 Active, 3 Activity ≤ 1 µM, 22 Tested

AID:: 95328

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9532918.

In vitro ATP-sensitive potassium channel (KATP) activity in cells expressing human KATP channels Kir6.2 and sulfonylurea receptor 2B

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 9; ...
Total:: 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 95329

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 9562319.

Percent inhibition of glibenclamide binding to K+ channel

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:7 Tested

AID:: 95623

Summary PubMed Citation Related BioAssays by Target

Select item 8001420.

Antiarrhythmic effect in Guinea pig papillary muscle KATP channel at 0.2 uM; ND=Not determined

Source:: ChEMBL

Protein Targets:: ATP-binding cassette sub-family C member 8; ...
Total:: 4

Assay data:1 Tested

AID:: 80014

Summary PubMed Citation Related BioAssays by Target

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Target

RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (36)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (3)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (27)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (38)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (61)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (59)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (14)
BioAssays deposited by other experimentalists

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BioAssay by Target (List) for Gene (Select 10060) (74)
PubChem BioAssay
Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Mus musculus]
Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 [Mus musculus]
Gene ID:11938

Gene
Gene Links for GEO Profiles (Select 76614857) (1)
Gene
Endothelial cell response to hypoxia and subsequent reoxygenation
Endothelial cell response to hypoxia and subsequent reoxygenation
Accession: GDS1968

GEO DataSets
Related DataSets for GEO Profiles (Select 22851312) (1)
GEO DataSets

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