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RNAi screen for vemurafenib enhancer genes in BRAFV600 melanoma - Primary Screen
Assay data:790 Active, 18119 Tested
Summary
Human ABCC5 (ABCC subfamily)
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced TNF-alpha response in human macrophages_Primary screen TNF readout
Assay data:2853 Active, 18113 Tested
SummaryRelated BioAssays by Same Project
Activity at MRP5 in human Colo-357 cells assessed as 5-FdUMP accumulation at 100 uM after 15 mins in presence of MRP inhibitor MK571
Assay data:1 Active, 1 Tested
Activity at MRP5 in human Colo-357 cells assessed as 5-FdUMP accumulation at 100 uM after 15 mins
Activity at MRP5 in human Colo-357 cells assessed as increase of drug efflux after 60 mins relative to wild type cells
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Activity at MRP5 in human Colo-357 cells assessed as decrease of drug accumulation after 2 hrs relative to wild type cells
A screen to identify synthetic lethal interactions with E-cadherin in an MCF10A isogenic cell line
Assay data:2442 Active, 18052 Tested
SummaryPubMed Citation
A screen to identify genes that regulate lymphatic endothelial cell migration - Primary Screen
Assay data:1034 Active, 18120 Tested
SummaryRelated BioAssays by Depositor
Identification of proteins required for the processing of the EWS-FLI1 nascent transcript
Assay data:59220 Tested
InfectX: Pathogen infection siRNA screens
Assay data:115372 Tested
A whole genome RNAi screen highlights components of the ER/Golgi as a prominent source of resistance to immunotoxin-mediated cytotoxicity
Assay data:555 Active, 64752 Tested
RNAi screen for vorinostat resistance genes - Primary Screen
Assay data:450 Active, 18118 Tested
Druggable Genome siRNA Screen for Enhancers of Camptothecin in MDA-MB-231 Breast Cancer Cells
Assay data:167 Active, 26449 Tested
TP_TRANSPORTER: RT-PCR in HepG2 cells
Assay data:3 Tested
TP_TRANSPORTER: inhibition of PMEA efflux (PMEA: 1 uM) in MRP5-expressing MDCKII cells
TP_TRANSPORTER: inhibition of alaninyl-d4TMP by Prostaglandin A1 at a concentration of 20uM in membrane vesicle from MRP5-expressing HEK293 cells
TP_TRANSPORTER: inhibition of alaninyl-d4TMP by Prostaglandin E1 at a concentration of 20uM in membrane vesicle from MRP5-expressing HEK293 cell
TP_TRANSPORTER: inhibition of alaninyl-d4TMP by Prostaglandin E2 at a concentration of 20uM in membrane vesicle from MRP5-expressing HEK293 cells
TP_TRANSPORTER: inhibition of alaninyl-d4TMP by Prostaglandin F2alpha at a concentration of 20uM in membrane vesicle from MRP5-expressing HEK293 cells
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