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Inhibition of HDAC in human HL60 cells assessed as upregulation of acetyl-alpha-tubulin levels after 24 hrs by Western blot analysis
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of HDAC in human HeLa-S3 cell lysates assessed as residual activity at 1.2 x 10'-4 M preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 35 mins by fluorimetric method relative to control
Inhibition of HDAC in human HeLa-S3 cell lysates assessed as residual activity at 1 x 10'-4 M preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 35 mins by fluorimetric method relative to control
Assay data:3 Tested
Inhibition of HDAC in human HeLa-S3 cell lysates assessed as residual activity at 1.6 x 10'-4 M preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 35 mins by fluorimetric method relative to control
Inhibition of HDAC in human HeLa-S3 cell lysates assessed as residual activity at 2 x 10'-4 M preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 35 mins by fluorimetric method relative to control
Inhibition of HDAC in human HeLa-S3 cell lysates assessed as residual activity at 3.2 x 10'-4 M preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 35 mins by fluorimetric method relative to control
Inhibition of HDAC in human HeLa-S3 cell lysates preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 35 mins by fluorimetric method
Assay data:4 Active, 1 Activity ≤ 1 µM, 9 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human recombinant HDAC5 using fluorogenic HDAC substrate class 2a after 30 mins by fluorimetrc method
Assay data:5 Active, 4 Activity ≤ 1 µM, 5 Tested
Inhibition of HDAC in human HL60 cells assessed as upregulation of acetylated histone H3 levels at 1 uM by Western blot analysis
Inhibition of HDAC in human HL60 cells assessed as upregulation of acetyl-alpha-tubulin levels at 1 uM by Western blot analysis
Inhibition of HDAC in human HL60 cells assessed as upregulation of acetylated histone H3 levels at 1 uM after 24 hrs by Western blot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of HDAC in human HL60 cells assessed as upregulation of acetyl-alpha-tubulin levels at 1 uM after 24 hrs by Western blot analysis
Inhibition of HDAC in human HL60 cells assessed as upregulation of acetyl-alpha-tubulin levels at 0.1 to 3 uM after 24 hrs by Western blot analysis
Inhibition of HDAC in human HL60 cells assessed as upregulation of acetylated histone H3 levels at 0.1 to 3 uM after 24 hrs by Western blot analysis
Inhibition of HDAC in human HL60 cells assessed as upregulation of acetyl-alpha-tubulin levels at 0.1 to 10 uM after 24 hrs by Western blot analysis
Inhibition of HDAC in human HL60 cells assessed as upregulation of acetylated histone H3 levels at 0.1 to 10 uM after 24 hrs by Western blot analysis
Inhibition of HDAC in human HeLa-S3 cell lysates assessed as residual activity at 8 x 10'-5 M preincubated for 15 mins followed by HDAC-Glo substrate addition measured after 35 mins by fluorimetric method relative to control
Assay data:2 Tested
Inhibition of HDAC in human HL60 cells assessed as upregulation of acetylated histone H3 levels after 24 hrs by Western blot analysis
Inhibition of HDAC in human HeLa nuclear extract using Ac-Lys(Ac)-pNA as substrate measured after 30 mins by fluorometric analysis
Assay data:6 Active, 7 Activity ≤ 1 µM, 10 Tested
Inhibition of HDAC in human HeLa cell nuclear extract using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 30 mins by fluorescence assay
Assay data:21 Active, 21 Activity ≤ 1 µM, 21 Tested
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