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Inhibition of Fatty acid synthase in chicken liver using [3H]-acetyl CoA as substrate preincubated for 30 mins followed by substrate addition and measured after 10 mins in presence of NADPH by scintillation counting analysis
Assay data:5 Tested
SummaryPubMed CitationRelated BioAssays by Target
Anti-angiogenesis activity in chicken embryo chorioallantoic membrane at 10 uM measured after 48 hrs by CAM assay
Assay data:1 Tested
SummaryPubMed Citation
Neuroprotective activity against chick sensory neuron assessed as neurite outgrowth
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Neuromuscular blocking activity in chicks assessed as induction of spastic paralysis by measuring time of onset of muscle relaxation at 0.15 mmol/Kg, ip administered as single dose
Neuromuscular blocking activity in chicks assessed as induction of flaccid paralysis by measuring time of onset of muscle relaxation at 0.15 mmol/Kg, ip administered as single dose
Assay data:3 Tested
Neuromuscular blocking activity in chicks assessed as induction of flaccid paralysis by measuring time of onset of head drop at 0.15 mmol/Kg, ip administered as single dose
Neuromuscular blocking activity in ip dosed chicks assessed as induction of spastic paralysis
Neuromuscular blocking activity in ip dosed chicks assessed as induction of flaccid paralysis
Substrate activity at chicken MCT3 expressed in yeast assessed as Km incubated for 3 mins by Michaelis-Menten analysis
Cytotoxicity against chicken heart fibroblast cells
Ex vivo antiangiogenesis activity in chicken embryo chorioallantonic membrane assessed as reduction in microvessel density at 5 to 20 nM measured after 48 hrs by stereomicroscopic analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Antagonist activity at Meleagris P2Y1R expressed in human 1321N1 cells assessed as inhibition of UDP-induced calcium mobilization at 100 uM by FLIPR assay relative to control
Cytotoxicity against chick embryo fibroblast cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay
Assay data:11 Tested
Cytotoxicity against chicken embryo fibroblasts assessed as reduction in cell viability after 48 hrs by CCK-8 assay
Assay data:28 Tested
Cytotoxicity against chicken embryo fibroblasts after 48 hrs by CCK-8 assay
Assay data:14 Tested
Cytotoxicity against chicken embryo fibroblasts assessed as reduction in cell viability after 2 days by CCK-8 assay
Assay data:2 Tested
Hemolytic activity in chicken RBC after 1 hr
Assay data:20 Activity ≤ 1 µM, 22 Tested
SummaryCompounds, activity ≤ 1 µM
In vivo agonist activity at dopamine receptor in pigeon assessed as induction of pecking behavior administered intramuscularly after 1 hr
Induction of pecking in pigeon at 1.62 umol/kg, im
Induction of pecking activity in pigeons assessed as counts for 1 hr
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