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Inhibition Assay from Article 10.1002/cbic.200900750: "Structural investigation of the binding of 5-substituted swainsonine analogues to Golgi alpha-mannosidase II."
Assay data:7 Active, 7 Activity ≤ 1 µM, 7 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition Assay from Article 10.1002/cbic.200800538: "The molecular basis of inhibition of Golgi alpha-mannosidase II by mannostatin A."
Assay data:4 Active, 4 Activity ≤ 1 µM, 6 Tested
Binding affinity to Laodelphax striatella (small brown planthopper) nicotinic acetylcholine receptor
Assay data:34 Active, 34 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Effect on Drosophila melanogaster Nav1 expressed in Xenopus laevis oocytes at 10 uM at holding potential of -90 mV by patch clamp electrophysiology
Assay data:1 Tested
SummaryPubMed Citation
Inhibition of Drosophila topoisomerase II assessed as relaxation of supercoiled plasmid pBR322 DNA incubated for 30 mins by ethidium bromide staining based agarose gel electrophoresis
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of Drosophila melanogaster Spastin N527C mutant (209 to 758 residues) in presence of ATP by NADH-coupled fluorescence assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of wild-type Drosophila melanogaster Spastin (209 to 758 residues) in presence of ATP by NADH-coupled fluorescence assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Agonist activity at Drosophila melanogaster sNPFR1 expressed in wild type CHO-K1 cells assessed as increase in calcium level at 0.1 mM after 20 secs by luminescence assay
Assay data:4 Tested
Agonist activity at Drosophila melanogaster NPFR1 expressed in wild type CHO-K1 cells assessed as increase in calcium level at 0.1 mM after 20 secs by luminescence assay
Insecticidal activity against wild type Drosophila melanogaster L. assessed as mortality compound topically applied dorsally to the thorax at 23 to 25 25 degC, 60 to 70%RH measured per adult after 3 hr
Assay data:5 Tested
Adulticidal activity against Drosophila melanogaster larvae assessed as mortality measured per adult
Assay data:3 Tested
Insecticidal activity against first-instar larval stage of Drosophila melanogaster fed with artificial diet containing compound assessed as mortality measured after 24 hr
Assay data:2 Tested
Summary
Insecticidal activity against first-instar larval stage of Drosophila melanogaster fed with artificial diet containing compound assessed as mortality measured after 72 hr
Assay data:6 Tested
Adulticidal activity against adult Drosophila melanogaster (males/females 1:1 ratio) assessed as mortality measured after 3 hr
Insecticidal activity against 5 to 7 days old adult Drosophila melanogaster assessed as mortality measured as inability to move compound treated in diet at 25 degC and >90% RH treated for 8 days
Ovicidal activity against Drosophila melanogaster egg by paper disk method
Photoovicidal activity against Drosophila melanogaster egg pretreated 1 hr before UV light irradiation for 45 mins by paper disk method
Insecticidal activity against Drosophila melanogaster after 40 hrs
Inhibition of FASN in one day old PINK1 mutant containing Drosophila melanogaster assessed as rescue of defective flight at 0.1 to 300 uM dosed with food incubated for 72 hrs
Inhibition of FASN in one day old PINK1 mutant containing Drosophila melanogaster assessed as rescue of defective flight at 100 to 300 uM dosed with food incubated for 72 hrs
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