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Toxicity in shrimp assessed as lethal dose
Assay data:5 Tested
SummaryPubMed Citation
NanoLuc Inhibition Assay from Article 10.1021/acschembio.6b01129: "Highly Potent Cell-Permeable and Impermeable NanoLuc Luciferase Inhibitors."
Assay data:41 Active, 29 Activity ≤ 1 µM, 47 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Induction of neurotoxicity in cray fish measured after 24 hrs
Assay data:2 Tested
Biomagnification factors in Diporeia
Assay data:19 Tested
The compound was tested for its ability to block the excitability of spider crab walking leg nerve bundles, the peak action potential amplitude, upon washing in physiological saline for 20 minutes.
Assay data:4 Tested
The compound was tested for optical responses recorded from spider crab walking leg nerve bundles upon staining.
Assay data:8 Tested
The compound was tested for its ability to block the excitability of spider crab walking leg nerve bundles, peak action potential amplitude, recorded by a pair of external Ag-AgCl electrodes.
Induction of depolarization in Procambarus clarkii (crayfish) giant axons assessed as transient inward sodium currents at -100 to -20 mV holding potential at 2 x 10 '-5 M
Assay data:5 Active, 5 Tested
SummaryCompounds, Active
Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB
Assay data:3598 Active, 421 Activity ≤ 1 nM, 2233 Activity ≤ 1 µM, 3598 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Experimentally measured binding affinity data derived from PDB
Assay data:3073 Active, 3073 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
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