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Cytotoxicity against Potorous tridactylus PtK2 cells after 5 days by MTT assay
Assay data:2 Tested
SummaryPubMed Citation
Cytotoxicity against Potorous tridactylus PtK2 cells by MTT assay
Assay data:2 Active, 2 Tested
SummaryCompounds, ActivePubMed Citation
Cytotoxicity against Potorous tridactylus PtK2 cells after 18 hrs by MTT assay
SummaryCompounds, Active
Growth inhibition of potorous tridactylus PtK2 cells after 48 hrs by MTT assay
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Growth inhibition of rat kangaroo PtK2 cells after 5 days by MTT assay
Assay data:9 Active, 6 Activity ≤ 1 µM, 10 Tested
Growth inhibition of Potorous tridactylus PtK2 cells
Assay data:9 Active, 1 Activity ≤ 1 nM, 9 Activity ≤ 1 µM, 9 Tested
Antiproliferative activity against rat kangaroo PtK2 cells after 48 hrs
Inhibition of tubulin polymerization in Potorous tridactylus Ptk2 cells assessed as destruction of microtubule network at 5 uM after 1 hr by immunofluorescence assay
Inhibition of polo-like kinase 1 activity in rat kangaroo PtK2 cells expressing GFP-labeled alpha-tubulin assessed as stable microtubule bundles at 6.3 uM at 20 sec time interval for 5 min by spinning disk confocal microscopy
Assay data:1 Active, 1 Tested
Inhibition of polo-like kinase 1 activity in rat kangaroo PtK2 cells expressing GFP-labeled alpha-tubulin assessed as V-shaped chromosome at 20 uM by spinning disk confocal microscopy in presence of 20 uM MG132
Inhibition of polo-like kinase 1 activity in rat kangaroo PtK2 cells expressing GFP-labeled alpha-tubulin assessed as shortening of chromosome associated microtubule fibres at 20 uM by spinning disk confocal microscopy in presence of 20 uM MG132
Inhibition of polo-like kinase 1 activity in rat kangaroo PtK2 cells expressing GFP-labeled alpha-tubulin assessed as V-shaped chromosome at 6.3 uM by spinning disk confocal microscopy in presence of 20 uM MG132
Inhibition of polo-like kinase 1 activity in rat kangaroo PtK2 cells expressing GFP-labeled alpha-tubulin assessed as shortening of chromosome associated microtubule fibres at 6.3 uM by spinning disk confocal microscopy in presence of 20 uM MG132
Inhibition of polo-like kinase 1 activity in rat kangaroo PtK2 cells expressing GFP-labeled alpha-tubulin assessed as phosphorylation of Cdc25c at 20 uM after 1 hr by quantitative immunofluorescence
Inhibition of polo-like kinase 1 activity in rat kangaroo PtK2 cells expressing GFP-labeled alpha-tubulin assessed as phosphorylation of Cdc25c at 6.3 uM after 1 hr by quantitative immunofluorescence
Antiproliferative activity against prometaphase PTK1 cells assessed as complete arrest at 1 mM within 50 mins
Antiproliferative activity against anaphase PTK1 cells assessed as delay in mitosis completion
Antimitotic activity in rat kangaroo PtK2 cells expressing GFP-labeled alpha-tubulin in presence of monastrol assessed as cells remained in mitosis at 6 uM after 90 mins by phase-contrast microscopy
Antimitotic activity in rat kangaroo PtK2 cells expressing GFP-labeled alpha-tubulin in presence of monastrol assessed as cells remained in mitosis at 20 uM after 90 mins by phase-contrast microscopy
Disruption of microtubule network in rat kangaroo PtK2 cells at 5 uM after 1 hr by immunofluorescence microscopic analysis
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