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Inhibition of recombinant renilla luciferase at 10 uM using coelenterazine as substrate incubated for 10 mins by luminescence based microplate reader analysis relative to control
Assay data:20 Tested
SummaryPubMed Citation
Inhibition of Renilla luciferase activity expressed in human MDA-MB-468 cells assessed as decrease in luminescence at 10 uM measured after 12 hrs by luminescence assay
Assay data:1 Tested
Inhibition of Renilla luciferase activity expressed in human HCT-116 cells assessed as decrease in luminescence at 10 uM measured after 12 hrs by luminescence assay
GSK_PKIS: Inhibition of Sea Pansy Luciferase (Data from PubChem: AID 652015) [NIH NCATS]
Assay data:11 Active, 4 Activity ≤ 1 nM, 4 Activity ≤ 1 µM, 366 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Inhibition of Renilla reniformis luciferase
Assay data:2 Active, 45 Tested
SummaryCompounds, ActivePubMed Citation
Inhibition of sea pansy luciferase after 20 mins by luminescence assay
SummaryPubMed CitationRelated BioAssays by Target
Activation of renilla luciferase expressed in HEK293T cells at 0.1 uM incubated for 14 to 16 hrs by reporter gene assay
Activation of renilla luciferase expressed in HEK293T cells at 3 uM incubated for 14 to 16 hrs by reporter gene assay
Activation of renilla luciferase expressed in HEK293T cells at 15 uM incubated for 14 to 16 hrs by reporter gene assay
Induction of Renilla reniformis luciferase activity at 10 uM relative to control
Assay data:4 Tested
Effect on renilla recombinant luciferase protein expressed in HEK293 cells at 10 uM after 24 hrs in presence of 10 uM cycloheximide by renilla luciferase reporter gene assay
Assay data:2 Active, 4 Tested
Effect on renilla recombinant luciferase protein
Effect on Renilla reniformis luciferase
Assay data:5 Tested
Inhibition of Renilla reniformis luciferase at 20 uM assessed as quenching of luminescence
Effect on renilla luciferase expressed in HEK293T cells at 6.25 to 50 uM after 48 hrs
Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB
Assay data:3598 Active, 421 Activity ≤ 1 nM, 2233 Activity ≤ 1 µM, 3598 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Experimentally measured binding affinity data derived from PDB
Assay data:3073 Active, 3073 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
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