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Antiviral activity against Rotavirus SA11 in MA104 cells assessed as inhibition of viral replication after 24 hrs by immunofluorescent assay and Western blotting analysis
Assay data:7 Active, 2 Activity ≤ 1 µM, 14 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Antiviral activity against gastrointestinal rotavirus in human Caco-2 cells assessed as inhibition of infectivity following virus attachment
Assay data:4 Tested
SummaryPubMed Citation
Antiviral activity against rotavirus RF in human Caco-2 cells assessed as inhibition of infectivity following virus attachment after 72 hrs
Assay data:5 Tested
Antiviral activity against Rotavirus RF in rhesus monkey MA104 cells assessed as inhibition of infectivity following virus attachment after 72 hrs
Assay data:3 Active, 5 Tested
SummaryCompounds, ActivePubMed Citation
Antiviral activity against Rotavirus RF infected in rhesus monkey MA104 cells assessed as neutralization of virus in solution before its attachment after 72 hrs
Assay data:2 Active, 5 Tested
Antiviral activity against Rotavirus RF in human Caco-2 cells assessed as inhibition of infectivity following virus attachment after 72 hrs
Antiviral activity against Rotavirus RF in human Caco-2 cells assessed as neutralization of virus in solution before its attachment after 72 hrs
Antiviral activity against rotavirus RF infected human Caco-2 cells following viral attachment after 72 hrs
Antiviral activity against rotavirus RF in human Caco-2 cells after neutralization of virus in solution pre-incubated with compound for 12 hrs before infection
Assay data:1 Active, 4 Tested
Inhibitory concentration against human rotavirus MO strain
Assay data:1 Tested
Virucidal activity against Rotavirus SA11 in MA104 cells assessed as reduction in viral titer at 100 uM pretreated for 2 hrs prior infection measured after 12 hrs postinfection by Western blotting analysis
Assay data:2 Tested
Virucidal activity against Rotavirus SA11 in MA104 cells assessed as reduction in viral titer at 100 uM pretreated for 2 hrs prior infection measured after 12 hrs postinfection by immunofluorescent assay
Antiviral activity against Rotavirus Wa in MA104 cells assessed as inhibition of viral replication after 24 hrs by immunofluorescent assay and Western blotting analysis
Assay data:6 Active, 6 Tested
Inhibition of Rotavirus Wa VP8-mediated binding to monkey MA104 cells at 10 mM after 1 hr by immunofluorescence assay in presence of sialidase
Assay data:1 Active, 1 Tested
Inhibition of Rotavirus Wa VP8-mediated infectivity in monkey MA104 cells at 10 mM after 1 hr by immunofluorescence assay
Inhibitory concentration against human rotavirus MO strain; No inhibition
Antiviral activity against rotavirus RF in human Caco-2 cells assessed as neutralization of virus before its attachment after 72 hrs
Antiviral activity against gastrointestinal rotavirus in human Caco-2 cells assessed as neutralization of virus in the solution before attachment
Antiviral activity against rotavirus by plaque reduction assay
Inhibitory activity against human Wa Rotavirus strain
Assay data:11 Tested
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