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Antiviral activity against Human adenovirus 2 infected in HEL cells assessed as reduction in virus-induced cytopathic effect by microscopic analysis
Assay data:6 Tested
SummaryPubMed Citation
Antiviral activity against Human adenovirus 5 Adenoid 75 infected in A549 cells assessed as reduction in virus titer preincubated for 24 hrs followed by viral infection and measured after 72 hrs by microscopic analysis
Assay data:39 Tested
Antiviral activity against Human adenovirus 5 Adenoid 75 infected in A549 cells assessed as inhibition of viral adsorption at early stage of replication treated for 1 hr during viral infection followed by replacement with fresh medium and measured after 72 hrs by MTT assay
Assay data:42 Tested
Antiviral activity against Human adenovirus 5 infected in human A549 cells
Assay data:2 Tested
Antiviral activity against wild-type Human adenovirus 5 infected in human A549 cells assessed as inhibition of viral DNA replication by measuring number of viral DNA copies at 9.3 uM after 24 hrs by RT-qPCR analysis (Rvb = 100 +/- 0.16 %)
Assay data:1 Tested
Antiviral activity against wild-type Human adenovirus 5 infected in human A549 cells assessed as inhibition of viral DNA replication by measuring number of viral DNA copies at 12 uM after 24 hrs by RT-qPCR analysis (Rvb = 100 +/- 0.16 %)
Antiviral activity against wild-type Human adenovirus 5 infected in human A549 cells assessed as inhibition of viral DNA replication by measuring number of viral DNA copies at 9 uM after 24 hrs by RT-qPCR analysis (Rvb = 100 +/- 0.16 %)
Antiviral activity against Human adenovirus 5 infected in 293beta5 cells assessed as inhibition of virus infection at 10 times IC50 measured after 10 to 20 mins by GFP reporter gene assay relative to control
Antiviral activity against Human adenovirus 5 infected in 293beta5 cells assessed as inhibition of virus infection at 10 fold IC50 measured after 5 mins by GFP reporter gene assay relative to control
Antiviral activity against Human adenovirus 5 infected in 293beta5 cells assessed as inhibition of virus infection at 10 fold of IC50 measured at 0 min by GFP reporter gene assay relative to control
Assay data:3 Tested
Antiviral activity against Human adenovirus 5 infected in 293beta5 cells assessed as inhibition of virus infection at 10 fold IC50 measured after 60 mins by GFP reporter gene assay relative to control
Antiviral activity against wild-type Human adenovirus 5 infected in human A549 cells assessed as inhibition of viral DNA replication by measuring number of viral DNA copies at 5 uM after 24 hrs by RT-qPCR analysis (Rvb = 100 +/- 0.16 %)
Antiviral activity against wild-type Human adenovirus 5 infected in human A549 cells assessed as as inhibition of viral entry by measuring nuclear associated viral genome level at 5 uM incubated for 45 mins by RT-PCR analysis (Rvb = 100 +/- 1.07 %)
Antiviral activity against wild-type Human adenovirus 5 infected in human A549 cells assessed as inhibition of viral DNA replication by measuring number of viral DNA copies at 2.7 uM after 24 hrs by RT-qPCR analysis (Rvb = 100 +/- 0.16 %)
Antiviral activity against wild-type Human adenovirus 5 infected in human A549 cells assessed as inhibition of viral entry by measuring nuclear associated viral genome level at 10 fold IC50 incubated for 45 mins by RT-PCR analysis (Rvb = 100 +/- 1.07 %)
Assay data:8 Tested
Antiviral activity against wild-type Human adenovirus 5 infected in human A549 cells assessed as inhibition of virus entry at 50 uM incubated for 48 hrs by fluorescence assay relative to control
Assay data:9 Tested
Antiviral activity against wild-type Human adenovirus 5 infected in human A549 cells assessed as inhibition of virus entry incubated for 48 hrs by fluorescence assay
Assay data:2 Active, 9 Tested
SummaryCompounds, ActivePubMed Citation
Antiviral activity against WT-Human adenovirus 5 infected in A549 cells assessed as fold reduction in virus yield at 10 fold of IC50 after 48 hrs endpoint dilution method
Antiviral activity against Human adenovirus 5 infected in 293beta5 cells assessed as inhibition of plaque formation at 10 uM incubated for 7 days by GFP reporter gene assay relative to control
Assay data:66 Tested
Antiviral activity against GFP-fused Human adenovirus 5 infected in 293beta5 cells assessed as inhibition of plaque formation incubated for 7 days by GFP reporter gene assay
Assay data:54 Active, 17 Activity ≤ 1 µM, 68 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
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