Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Binding affinity to Kaposi's sarcoma herpesvirus C-terminal His-tagged oligomerization deficient LANA DBD (1008 to 1146 residues) K1055E/K1138S/K1140D/K1141D/R1039Q/R1040Q/A1121E/K1109A/D1110A mutant expressed in Escherichia coli BL21(DE3) at 500 uM by STD-NMR analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Inhibition of Kaposi's sarcoma herpesvirus wild type LANA CTD (934 to 1162 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition of LANA interaction with 5'-Dy682-labeled viral DNA LBS1 probe preincubated with LANA CTD for 60 mins followed by addition of DNA probe and measured after 30 mins by Electrophoretic mobility shift assay
Assay data:2 Tested
SummaryPubMed Citation
Inhibition of Kaposi's sarcoma herpesvirus C-terminal His-tagged oligomerization deficient LANA DBD (1008 to 1146 residues) K1055E/K1138S/K1140D/K1141D/R1039Q/R1040Q/A1121E/K1109A/D1110A mutant expressed in Escherichia coli BL21(DE3) assessed as inhibition of LANA interaction with 5'-Dy682-labeled viral DNA LBS1 probe at 250 uM preincubated with LANA-DBD for 60 mins followed by addition of DNA probe and measured after 30 mins by Electrophoretic mobility shift assay
Assay data:3 Tested
Inhibition of Kaposi's sarcoma herpesvirus C-terminal His-tagged oligomerization deficient LANA DBD (1008 to 1146 residues) K1055E/K1138S/K1140D/K1141D/R1039Q/R1040Q/A1121E/K1109A/D1110A mutant expressed in Escherichia coli BL21(DE3) assessed as inhibition of LANA interaction with fluorescently-labelled viral DNA LBS2 probe at 500 uM preincubated with LANA-DBD for 60 mins followed by addition of DNA probe and measured after 90 mins by flourescence polarization assay
Assay data:15 Tested
Inhibition of Kaposi's sarcoma herpesvirus C-terminal His-tagged oligomerization deficient LANA DBD (1008 to 1146 residues) K1055E/K1138S/K1140D/K1141D/R1039Q/R1040Q/A1121E/K1109A/D1110A mutant expressed in Escherichia coli BL21(DE3) assessed as inhibition of LANA interaction with 5'-Dy682-labeled viral DNA LBS1+2+3 probe at 125 uM preincubated with LANA-DBD for 60 mins followed by addition of DNA probe and measured after 30 mins by Electrophoretic mobility shift assay
Inhibition of Kaposi's sarcoma herpesvirus C-terminal His-tagged oligomerization deficient LANA DBD (1008 to 1146 residues) K1055E/K1138S/K1140D/K1141D/R1039Q/R1040Q/A1121E/K1109A/D1110A mutant expressed in Escherichia coli BL21(DE3) assessed as inhibition of LANA interaction with 5'-Dy682-labeled viral DNA LBS1+2 probe at 62.5 uM preincubated with LANA-DBD for 60 mins followed by addition of DNA probe and measured after 30 mins by Electrophoretic mobility shift assay
Inhibition of Kaposi's sarcoma herpesvirus wild type LANA CTD (934 to 1162 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition of LANA interaction with 5'-Dy682-labeled viral DNA LBS1 probe at 250 uM preincubated with LANA CTD for 60 mins followed by addition of DNA probe and measured after 30 mins by Electrophoretic mobility shift assay
Assay data:1 Active, 8 Tested
Inhibition of Kaposi's sarcoma herpesvirus C-terminal His-tagged oligomerization deficient LANA DBD (1008 to 1146 residues) K1055E/K1138S/K1140D/K1141D/R1039Q/R1040Q/A1121E/K1109A/D1110A mutant expressed in Escherichia coli BL21(DE3) assessed as inhibition of LANA interaction with 5'-Dy682-labeled viral DNA LBS1 probe preincubated with LANA-DBD for 60 mins followed by addition of DNA probe and measured after 30 mins by Electrophoretic mobility shift assay
Assay data:5 Tested
Inhibition of Kaposi's sarcoma herpesvirus C-terminal His-tagged oligomerization deficient LANA DBD (1008 to 1146 residues) K1055E/K1138S/K1140D/K1141D/R1039Q/R1040Q/A1121E/K1109A/D1110A mutant expressed in Escherichia coli BL21(DE3) assessed as inhibition of LANA interaction with fluorescently-labelled viral DNA LBS3 probe preincubated with LANA-DBD for 60 mins followed by addition of DNA probe and measured after 90 mins by flourescence polarization assay
Inhibition of Kaposi's sarcoma herpesvirus C-terminal His-tagged oligomerization deficient LANA DBD (1008 to 1146 residues) K1055E/K1138S/K1140D/K1141D/R1039Q/R1040Q/A1121E/K1109A/D1110A mutant expressed in Escherichia coli BL21(DE3) assessed as inhibition of LANA interaction with 5'-Dy682-labeled viral DNA LBS1 probe at 500 uM preincubated with LANA-DBD for 60 mins followed by addition of DNA probe and measured after 30 mins by Electrophoretic mobility shift assay
Assay data:44 Tested
Inhibition of Kaposi's sarcoma herpesvirus C-terminal His-tagged oligomerization deficient LANA DBD (1008 to 1146 residues) K1055E/K1138S/K1140D/K1141D/R1039Q/R1040Q/A1121E/K1109A/D1110A mutant expressed in Escherichia coli BL21(DE3) assessed as inhibition of LANA interaction with fluorescently-labelled viral DNA LBS2 probe preincubated with LANA-DBD for 60 mins followed by addition of DNA probe and measured after 90 mins by flourescence polarization assay
Assay data:1 Active, 38 Tested
Inhibition of Kaposi's sarcoma herpesvirus C-terminal His-tagged oligomerization deficient LANA DBD (1008 to 1146 residues) K1055E/K1138S/K1140D/K1141D/R1039Q/R1040Q/A1121E/K1109A/D1110A mutant expressed in Escherichia coli BL21(DE3) assessed as inhibition of LANA interaction with fluorescently-labelled viral DNA LBS1 probe preincubated with LANA-DBD for 60 mins followed by addition of DNA probe and measured after 90 mins by flourescence polarization assay
Binding affinity to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) at 1 mM by STD-NMR analysis
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of 5'-Dy682-labelled LBS1 DNA binding to GST-tagged LANA C-terminal domain (934 to 1162 residues) preincubated for 1 hr followed by 5'-Dy682-labelled LBS1 DNA addition and measured after 30 mins by electrophoretic mobility shift assay
Assay data:1 Tested
Inhibition of 5'-Dy682-labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) preincubated for 1 hr followed by 5'-Dy682-labelled LBS1 DNA addition and measured after 30 mins by electrophoretic mobility shift assay
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of 5'-Dy682-labelled LBS1/LBS2 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) at 500 uM preincubated for 1 hr followed by 5'-Dy682-labelled LBS1 DNA addition and measured after 30 mins by electrophoretic mobility shift assay
Assay data:4 Active, 6 Tested
Binding affinity to human herpesvirus human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) by microscale thermophoresis assay
Inhibition of 5'-Dy682-labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) at 500 uM preincubated for 1 hr followed by 5'-Dy682-labelled LBS1 DNA addition and measured after 30 mins by electrophoretic mobility shift assay
Inhibition of fluorescent labelled LBS3 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) preincubated for 60 mins followed by fluorescent labelled LBS2 addition and measured after 90 mins by fluorescence polarization assay
Assay data:6 Tested
Inhibition of fluorescent labelled LBS1 DNA binding to human herpesvirus 8 C-terminal His-tagged LANA oligomerization deficient mutant DBD (1008 to 1146 residues) expressed in Escherichia coli BL21 (DE3) preincubated for 60 mins followed by fluorescent labelled LBS2 addition and measured after 90 mins by fluorescence polarization assay
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on