Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
CDK6/CyclinD1 Kinase Inhibitory Activity Assay from US Patent US20240166635: "AMINOHETEROARYL KINASE INHIBITORS"
Assay data:124 Active, 133 Activity ≤ 1 µM, 133 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Human P2X7 Channel Calcium-Influx Assay from US Patent US20240034737: "Heterocyclic Derivatives as P2X7 Receptor Antagonists"
Assay data:103 Active, 103 Activity ≤ 1 µM, 103 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Mu-Opioid Receptor Activity Assay from US Patent US20240092802: "MU-OPIOID RECEPTOR AGONISTS AND USES THEREFOR"
Assay data:68 Active, 18 Activity ≤ 1 µM, 77 Tested
Inhibitory Activity Against KHK In Vitro from US Patent US20240067633: "KETOHEXOKINASE INHIBITOR AND USE THEREOF"
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
Glosensor cAMP assay from US Patent US20240059655: "HETEROCYCLIC G-PROTEIN-COUPLED RECEPTOR 52 (GPR52) AGONISTS"
Assay data:69 Active, 62 Activity ≤ 1 µM, 69 Tested
cell-based NF-kB reporter assay from US Patent US11905258: "2-aminoaryl-5-aryloxazole analogs for the treatment of neurodegenerative diseases"
Assay data:29 Active, 10 Activity ≤ 1 µM, 36 Tested
DHODH Kinetic Analysis from US Patent US11903936: "Anti-malarial agents"
Assay data:13 Active, 13 Activity ≤ 1 µM, 13 Tested
Antitumor activity against mouse MC38 tumor model administered as monotherapy
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
[3H] 2-OG cleavage activity assay (mouse brain)
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Mouse GCS enzymatic assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 2 Tested
Interleukin IL-1 Eurofins Panlabs panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Nitric Oxide Synthetase, Inducible (iNOS) Eurofins Panlabs panel
Cellular PDE9A assay
SummaryCompounds, ActiveCompounds, activity ≤ 1 µM
Inhibition of M-1 water resorption
SummaryCompounds, ActiveRelated BioAssays by Target
Enzymatic assay (mHSD17B13)
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 2 Tested
Antihypercholesterolemic activity against hApoB100/hCETP-dTg hypercholesterolemic mouse model assessed as serum non-HDL-C level at 3 mg/kg, po administered once daily for 8 days
Assay data:5 Tested
SummaryPubMed Citation
Antihypercholesterolemic activity against hApoB100/hCETP-dTg hypercholesterolemic mouse model assessed as serum total cholesterol level at 3 mg/kg, po administered once daily for 8 days
Antihypercholesterolemic activity against hApoB100/hCETP-dTg hypercholesterolemic mouse model assessed as serum HDL-C level at 3 mg/kg, po administered once daily for 8 days
Selectivity ratio of EC50 for agonist activity at Gal4-fused mouse PPAR-gamma ligand binding domain expressed in CHO-K1 cells to EC50 for agonist activity at Gal4-fused mouse PPAR-delta ligand binding domain expressed in CHO-K1 cells
Assay data:23 Tested
Agonist activity at Gal4-fused mouse PPAR-gamma ligand binding domain expressed in CHO-K1 cells assessed as receptor transactivation incubated for 24 to 48 hrs by luciferase reporter gene assay relative to control
SummaryPubMed CitationRelated BioAssays by Target
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on