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Binding affinity to N-terminal His6-tagged human SETDB1 Tudor domain (197 to 403 residues) expressed in Escherichia coli BL21(DE3)-pRARE2 cells by ITC assay
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Binding affinity to N-terminally biotinylated human SETDB1 Tudor domain (197 to 403 residues) expressed in Escherichia coli BL21(DE3)-pRARE2 cells by SPR analysis
Assay data:8 Tested
Binding affinity to N-terminal His6-tagged human SETDB1 Tudor domain (197 to 403 residues) expressed in Escherichia coli BL21(DE3)-pRARE2 cells assessed as induction of HSQC shift at 5 mM by 1H-15 N HSQC-TROSY NMR spectroscopy
Assay data:4 Active, 6 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Binding affinity to N-terminal His6-tagged human SETDB1 Tudor domain (197 to 403 residues) expressed in Escherichia coli BL21(DE3)-pRARE2 cells assessed as induction of HSQC shift at 10 mM by 1H-15 N HSQC-TROSY NMR spectroscopy
Assay data:1 Tested
Selectivity interaction (Methyltransferase panel (Scintillation proximity assay (SPA))) EUB0000212b SETDB1
SummaryRelated BioAssays by Target
Selectivity interaction (Methyltransferase panel) EUB0000196bCl SETDB1
Selectivity interaction (Methyltransferase panel (radioactive enzyme assay)) EUB0000216b SETDB1
Selectivity interaction (HMT panel) EUB0000194b SETDB1
Selectivity interaction (Protein methyltransferase panel (activity assay)) EUB0000211b SETDB1
Genome-wide Screen to Identify Regulators of Heterochromatin Recruitment or Maintenance
Assay data:403 Active, 24006 Tested
SummaryPubMed Citation
CRACM1 Is a Plasma Membrane Protein Essential for Store-Operated Ca2+ Entry
Assay data:2069 Active, 19730 Tested
MAPK Signaling Pathway Screen
Assay data:1643 Active, 22533 Tested
Genes involved in store-operated calcium entry
Assay data:75 Active, 22913 Tested
Genes involved in protein secretion and Golgi organization
Assay data:1068 Active, 22533 Tested
Hh Signalling
Assay data:503 Active, 21305 Tested
Functional genomic analysis of the Wnt-Wingless Signaling Pathway
Assay data:233 Active, 21998 Tested
Factors affecting human androgen receptor transcriptional activation
Assay data:246 Active, 23856 Tested
A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression
Assay data:18 Active, 21306 Tested
A genome-wide RNAi screen reveals multiple regulators of caspase activation
Assay data:47 Active, 19084 Tested
Neuronal and Glial Development
Assay data:135 Active, 2570 Tested
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