214629 214628 282917 214627 214626 214630 329747 329748 52104 52099 49 - PubChem BioAssay - NCBI

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Items: 17

Select item 3297491.

Agonist activity at mouse delta opioid receptor in mouse model

Source:: ChEMBL

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 329749

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 3297482.

Agonist activity at mu opioid receptor in mouse model

Source:: ChEMBL

Assay data:2 Active, 1 Activity ≤ 1 nM, 2 Activity ≤ 1 µM, 2 Tested

AID:: 329748

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation

Select item 521003.

Compound was tested for the inhibitory activity against chitin synthetase in the permeabilised cell assay

Source:: ChEMBL

Protein Target:: Chitin synthase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 8 Tested

AID:: 52100

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 520994.

Compound was tested for the inhibitory activity against chitin synthetase in the mixed membrane preparation from Candida albicans

Source:: ChEMBL

Protein Target:: Chitin synthase 1

Assay data:1 Active, 8 Tested

AID:: 52099

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 3297475.

Inhibition of human tripeptidyl peptidase2 from erythrocytes

Source:: ChEMBL

Protein Target:: Tripeptidyl-peptidase 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 329747

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 2829176.

Inhibition of TPPII in rat cerebral membrane

Source:: ChEMBL

Protein Target:: Tripeptidyl-peptidase 2

Assay data:25 Active, 15 Activity ≤ 1 µM, 36 Tested

AID:: 282917

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 2146307.

Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.

Source:: ChEMBL

Protein Target:: Tripeptidyl-peptidase 2

Assay data:13 Active, 11 Activity ≤ 1 µM, 21 Tested

AID:: 214630

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 2146298.

Inhibition potency against Cholecystokinin-8-Inactivating Peptidase (Serine Peptidase).

Source:: ChEMBL

Protein Target:: Tripeptidyl-peptidase 2

Assay data:4 Active, 1 Activity ≤ 1 µM, 59 Tested

AID:: 214629

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 2146279.

Inhibitory activity against tripeptidyl peptidase II purified from rat liver

Source:: ChEMBL

Protein Target:: Tripeptidyl-peptidase 2

Assay data:5 Active, 5 Activity ≤ 1 µM, 8 Tested

AID:: 214627

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 21462610.

Inhibition of Tripeptidyl-peptidase II purified from a rat liver post-lysosomal fraction.

Source:: ChEMBL

Protein Target:: Tripeptidyl-peptidase 2

Assay data:12 Active, 8 Activity ≤ 1 µM, 15 Tested

AID:: 214626

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 5210511.

Inhibition constant (KI) for the mmf chitin synthetase assay performed at constant inhibitor and varying substrate concentrations

Source:: ChEMBL

Protein Target:: Chitin synthase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 5 Tested

AID:: 52105

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 5210412.

Compound was tested for the inhibitory activity against chitin synthetase

Source:: ChEMBL

Protein Target:: Chitin synthase 1

Assay data:1 Active, 3 Tested

AID:: 52104

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 4757413.

Millimolar concentration at which some morphological effects in Candida albicans cells (about 5% of cells) was determined

Source:: ChEMBL

Assay data:8 Tested

AID:: 47574

Summary PubMed Citation

Select item 21462814.

Inhibition potency against Cholecystokinin-8-Inactivating Peptidase (Serine Peptidase).

Source:: ChEMBL

Protein Target:: Tripeptidyl-peptidase 2

Assay data:1 Tested

AID:: 214628

Summary PubMed Citation Related BioAssays by Target

Select item 4945015.

Concentration at which 50% of the Candida albicans cells were not viable

Source:: ChEMBL

Assay data:5 Tested

AID:: 49450

Summary PubMed Citation

Select item 4944716.

Compound was tested for the inhibitory activity against Candida albicans cell growth

Source:: ChEMBL

Assay data:3 Tested

AID:: 49447

Summary PubMed Citation

Select item 4856317.

Millimolar concentration of the lowest concentration that clearly inhibited the cell growth of Candida albicans was determined

Source:: ChEMBL

Assay data:8 Tested

AID:: 48563

Summary PubMed Citation

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BioActivity

Active Compounds (12)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (2)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (10)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (17)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (17)
BioAssays extracted from the literature

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214629 214628 282917 214627 214626 214630 329747 329748 52104 520... (17)
214629 214628 282917 214627 214626 214630 329747 329748 52104 52099 49450 49447 47574 329749 52105 52100 48563[uid]
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PubChem BioAssay
non-histone chromosomal protein HMG-17 [Bos taurus]
non-histone chromosomal protein HMG-17 [Bos taurus]
gi|149642941|ref|NP_001092415.1|

Protein
RecName: Full=Alanine--tRNA ligase, cytoplasmic; AltName: Full=Alanyl-tRNA synth...
RecName: Full=Alanine--tRNA ligase, cytoplasmic; AltName: Full=Alanyl-tRNA synthetase; Short=AlaRS; AltName: Full=Protein lactyltransferase AARS1; AltName: Full=Renal carcinoma antigen NY-REN-42
gi|115502460|sp|P49588.2|SYAC_HUMAN

Protein

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