Homo sapiens checkpoint kinase 2 (CHEK2), transcript variant 2, mRNA

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Germline CHEK2 mutations in patients with myeloid neoplasms. [Leukemia. 2024]
Germline CHEK2 mutations in patients with myeloid neoplasms.
Freiman L, Larcher L, Tueur G, Vasquez N, Da Costa M, Duchmann M, Raffoux E, Adès L, Fenaux P, Soulier J, et al. Leukemia. 2024 Apr; 38(4):908-911. Epub 2024 Feb 20.
CHEK2 germline variants identified in familial nonmedullary thyroid cancer lead to impaired protein structure and function. [J Biol Chem. 2024]
CHEK2 germline variants identified in familial nonmedullary thyroid cancer lead to impaired protein structure and function.
Pires C, Marques IJ, Valério M, Saramago A, Santo PE, Santos S, Silva M, Moura MM, Matos J, Pereira T, et al. J Biol Chem. 2024 Mar; 300(3):105767. Epub 2024 Feb 16.
Comprehensive splicing analysis of the alternatively spliced CHEK2 exons 8 and 10 reveals three enhancer/silencer-rich regions and 38 spliceogenic variants. [J Pathol. 2024]
Comprehensive splicing analysis of the alternatively spliced CHEK2 exons 8 and 10 reveals three enhancer/silencer-rich regions and 38 spliceogenic variants.
Sanoguera-Miralles L, Llinares-Burguet I, Bueno-Martínez E, Ramadane-Morchadi L, Stuani C, Valenzuela-Palomo A, García-Álvarez A, Pérez-Segura P, Buratti E, de la Hoya M, et al. J Pathol. 2024 Apr; 262(4):395-409. Epub 2024 Feb 9.

RefSeq alternative splicing
See 35 reference mRNA sequence splice variants for the CHEK2 gene.
RefSeq protein product
See the reference protein sequence for serine/threonine-protein kinase Chk2 isoform b (NP_665861.1).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
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Annotated Genomic
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Functional Class
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OMIM
OMIM records associated with Nucleotide sequence
PubMed (RefSeq)
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SNP
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GEO Profiles
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