Homo sapiens presenilin 2 (PSEN2), transcript variant 2, mRNA

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Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Presenilin Gene Mutation-associated Psychosis: Phenotypic Characteristics and Clinical Implications. [Alzheimer Dis Assoc Disord. 2024]
Presenilin Gene Mutation-associated Psychosis: Phenotypic Characteristics and Clinical Implications.
Colijn MA, Ismail Z. Alzheimer Dis Assoc Disord. 2024 Jan-Mar 01; 38(1):101-106. Epub 2024 Jan 17.
Quantitative comparison of presenilin protein expression reveals greater activity of PS2-γ-secretase. [FASEB J. 2024]
Quantitative comparison of presenilin protein expression reveals greater activity of PS2-γ-secretase.
Eccles MK, Main N, Carlessi R, Armstrong AM, Sabale M, Roberts-Mok B, Tirnitz-Parker JEE, Agostino M, Groth D, Fraser PE, et al. FASEB J. 2024 Jan; 38(1):e23396.
Cerebral organoids derived from patients with Alzheimer's disease with PSEN1/2 mutations have defective tissue patterning and altered development. [Cell Rep. 2023]
Cerebral organoids derived from patients with Alzheimer's disease with PSEN1/2 mutations have defective tissue patterning and altered development.
Vanova T, Sedmik J, Raska J, Amruz Cerna K, Taus P, Pospisilova V, Nezvedova M, Fedorova V, Kadakova S, Klimova H, et al. Cell Rep. 2023 Nov 28; 42(11):113310. Epub 2023 Oct 20.

RefSeq alternative splicing
See 12 reference mRNA sequence splice variants for the PSEN2 gene.
RefSeq protein product
See the reference protein sequence for presenilin-2 isoform 2 (NP_036618.2).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
Taxonomy sequences associated with Nucleotide record
Annotated Genomic
Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
BioSystems
BioSystems
CCDS
Link to Consensus CDS
Components (Core)
Links to Core components
Functional Class
Functional class of the sequence domain architecture
Gene
Link to related Genes
OMIM
OMIM records associated with Nucleotide sequence
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed

Ensembl [Ensembl]
Ensembl
presenilin 2 [Guide to Pharmacology]
presenilin 2
Guide to Pharmacology
GenScript latest version of gene cDNA ORF Clone [GenScript latest version of g...]
GenScript latest version of gene cDNA ORF Clone
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