Homo sapiens DNA polymerase epsilon, catalytic subunit (POLE), mRNA

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The P286R mutation of DNA polymerase ε activates cancer-cell-intrinsic immunity and suppresses endometrial tumorigenesis via the cGAS-STING pathway. [Cell Death Dis. 2024]
The P286R mutation of DNA polymerase ε activates cancer-cell-intrinsic immunity and suppresses endometrial tumorigenesis via the cGAS-STING pathway.
Tang M, Yin S, Zeng H, Huang A, Huang Y, Hu Z, Shah AR, Zhang S, Li H, Chen G. Cell Death Dis. 2024 Jan 18; 15(1):69. Epub 2024 Jan 18.
Race, Prevalence of POLE and POLD1 Alterations, and Survival Among Patients With Endometrial Cancer. [JAMA Netw Open. 2024]
Race, Prevalence of POLE and POLD1 Alterations, and Survival Among Patients With Endometrial Cancer.
Zheng S, Donnelly ED, Strauss JB. JAMA Netw Open. 2024 Jan 2; 7(1):e2351906. Epub 2024 Jan 2.
Cervical Cytology Preserves Histologically Detected Surface Epithelial Slackening, Unique to the POLE Mutation-subtype in Endometrial Cancer. [In Vivo. 2024]
Cervical Cytology Preserves Histologically Detected Surface Epithelial Slackening, Unique to the POLE Mutation-subtype in Endometrial Cancer.
Kitazono I, Akahane T, Yokoyama S, Kubota E, Nishida-Kirita Y, Noguchi H, Murakami M, Yanazume S, Kobayashi H, Tanimoto A. In Vivo. 2024 Jan-Feb; 38(1):321-333.

RefSeq alternative splicing
See 11 reference mRNA sequence splice variants for the POLE gene.
RefSeq protein product
See the reference protein sequence for DNA polymerase epsilon catalytic subunit A (NP_006222.2).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
Taxonomy sequences associated with Nucleotide record
Annotated Genomic
Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
BioSystems
BioSystems
CCDS
Link to Consensus CDS
Components (Core)
Links to Core components
Full text in PMC
Free full text articles in PMC
Functional Class
Functional class of the sequence domain architecture
Gene
Link to related Genes
OMIM
OMIM records associated with Nucleotide sequence
Probe
Related Probe entry
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed

Ensembl [Ensembl]
Ensembl
GenScript latest version of gene cDNA ORF Clone [GenScript latest version of g...]
GenScript latest version of gene cDNA ORF Clone
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