Homo sapiens milk fat globule EGF and factor V/VIII domain containing - Nucleotide

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MFG-E8 induces epithelial-mesenchymal transition and anoikis resistance to promote the metastasis of pancreatic cancer cells. [Eur J Pharmacol. 2024]
MFG-E8 induces epithelial-mesenchymal transition and anoikis resistance to promote the metastasis of pancreatic cancer cells.
Liu W, Ren Y, Wang T, Wang M, Xu Y, Zhang J, Bi J, Wu Z, Lv Y, Wu R. Eur J Pharmacol. 2024 Apr 15; 969:176462. Epub 2024 Feb 29.
Potent CTLs can be induced against tumor cells in an environment of lower levels of systemic MFG-E8. [Cancer Sci. 2024]
Potent CTLs can be induced against tumor cells in an environment of lower levels of systemic MFG-E8.
Mizote Y, Inoue T, Akazawa T, Kunimasa K, Tamiya M, Kumamoto Y, Tsuda A, Yoshida S, Tatsumi K, Ekawa T, et al. Cancer Sci. 2024 Apr; 115(4):1114-1128. Epub 2024 Feb 8.
PTP1B mediates the inhibitory effect of MFGE8 on insulin signaling through the β5 integrin. [J Biol Chem. 2024]
PTP1B mediates the inhibitory effect of MFGE8 on insulin signaling through the β5 integrin.
Datta R, Mukherjee D, Podolsky MJ, Yang CD, Alba DL, Singh S, Arnold TD, Koliwad S, Lizama CO, Atabai K. J Biol Chem. 2024 Feb; 300(2):105631. Epub 2024 Jan 8.

RefSeq alternative splicing
See 13 reference mRNA sequence splice variants for the MFGE8 gene.
RefSeq protein product
See the reference protein sequence for lactadherin isoform a preproprotein (NP_005919.2).

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Protein sequence from Nucleotide coding region
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Nucleotide