Homo sapiens insulin induced gene 1 (INSIG1), transcript variant 1, mR - Nucleotide

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A novel protein encoded by circINSIG1 reprograms cholesterol metabolism by promoting the ubiquitin-dependent degradation of INSIG1 in colorectal cancer. [Mol Cancer. 2023]
A novel protein encoded by circINSIG1 reprograms cholesterol metabolism by promoting the ubiquitin-dependent degradation of INSIG1 in colorectal cancer.
Xiong L, Liu HS, Zhou C, Yang X, Huang L, Jie HQ, Zeng ZW, Zheng XB, Li WX, Liu ZZ, et al. Mol Cancer. 2023 Apr 22; 22(1):72. Epub 2023 Apr 22.
Insulin-induced genes INSIG1 and INSIG2 mediate oxysterol-dependent activation of the PERK-eIF2α-ATF4 axis. [J Biol Chem. 2021]
Insulin-induced genes INSIG1 and INSIG2 mediate oxysterol-dependent activation of the PERK-eIF2α-ATF4 axis.
Watanabe Y, Sasaki T, Miyoshi S, Shimizu M, Yamauchi Y, Sato R. J Biol Chem. 2021 Aug; 297(2):100989. Epub 2021 Jul 21.
The Propensity of the Human Liver to Form Large Lipid Droplets Is Associated with PNPLA3 Polymorphism, Reduced INSIG1 and NPC1L1 Expression and Increased Fibrogenetic Capacity. [Int J Mol Sci. 2021]
The Propensity of the Human Liver to Form Large Lipid Droplets Is Associated with PNPLA3 Polymorphism, Reduced INSIG1 and NPC1L1 Expression and Increased Fibrogenetic Capacity.
Ferri F, Carotti S, Carpino G, Mischitelli M, Cantafora A, Molinaro A, Argenziano ME, Parisse S, Corsi A, Riminucci M, et al. Int J Mol Sci. 2021 Jun 5; 22(11). Epub 2021 Jun 5.

RefSeq alternative splicing
See 8 reference mRNA sequence splice variants for the INSIG1 gene.
RefSeq protein product
See the reference protein sequence for insulin-induced gene 1 protein isoform 1 (NP_005533.2).

Protein
Protein sequence from Nucleotide coding region
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Nucleotide