Homo sapiens DNA topoisomerase III alpha (TOP3A), transcript variant 1 - Nucleotide

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Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability. [Mol Syst Biol. 2024]
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.
Lü Y, Cho T, Mukherjee S, Suarez CF, Gonzalez-Foutel NS, Malik A, Martinez S, Dervovic D, Oh RH, Langille E, et al. Mol Syst Biol. 2024 Jun; 20(6):719-740. Epub 2024 Apr 5.
Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7. [Mol Oncol. 2024]
Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.
Baxter JS, Brough R, Krastev DB, Song F, Sridhar S, Gulati A, Alexander J, Roumeliotis TI, Kozik Z, Choudhary JS, et al. Mol Oncol. 2024 Feb; 18(2):369-385. Epub 2023 Oct 22.
Pathological variants in TOP3A cause distinct disorders of mitochondrial and nuclear genome stability. [EMBO Mol Med. 2023]
Pathological variants in TOP3A cause distinct disorders of mitochondrial and nuclear genome stability.
Erdinc D, Rodríguez-Luis A, Fassad MR, Mackenzie S, Watson CM, Valenzuela S, Xie X, Menger KE, Sergeant K, Craig K, et al. EMBO Mol Med. 2023 May 8; 15(5):e16775. Epub 2023 Apr 4.

RefSeq alternative splicing
See 11 reference mRNA sequence splice variants for the TOP3A gene.
RefSeq protein product
See the reference protein sequence for DNA topoisomerase 3-alpha isoform 1 (NP_004609.1).

Protein
Protein sequence from Nucleotide coding region
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GenScript latest version of gene cDNA ORF Clone [GenScript latest version of g...]
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Nucleotide