Homo sapiens phospholipase C gamma 2 (PLCG2), transcript variant 1, mR - Nucleotide

Analyze this sequence

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Pick Primers
Design and test primers for this sequence using Primer-BLAST.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Articles about the PLCG2 gene

The hypermorphic PLCγ2 S707Y variant dysregulates microglial cell function - Insight into PLCγ2 activation in brain health and disease, and opportunities for therapeutic modulation. [Biochim Biophys Acta Mol Basis...]
The hypermorphic PLCγ2 S707Y variant dysregulates microglial cell function - Insight into PLCγ2 activation in brain health and disease, and opportunities for therapeutic modulation.
Bull D, Matte JC, Navarron CM, McIntyre R, Whiting P, Katan M, Ducotterd F, Magno L. Biochim Biophys Acta Mol Basis Dis. 2024 Feb; 1870(2):166978. Epub 2023 Dec 6.
Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability. [Cell. 2023]
Antagonistic roles of canonical and Alternative-RPA in disease-associated tandem CAG repeat instability.
Gall-Duncan T, Luo J, Jurkovic CM, Fischer LA, Fujita K, Deshmukh AL, Harding RJ, Tran S, Mehkary M, Li V, et al. Cell. 2023 Oct 26; 186(22):4898-4919.e25. Epub 2023 Oct 11.
PLCG2-associated immune dysregulation (PLAID) comprises broad and distinct clinical presentations related to functional classes of genetic variants. [J Allergy Clin Immunol. 2024]
PLCG2-associated immune dysregulation (PLAID) comprises broad and distinct clinical presentations related to functional classes of genetic variants.
Baysac K, Sun G, Nakano H, Schmitz EG, Cruz AC, Fisher C, Bailey AC, PLCG2-Immune Dysregulation Working Group, Mace E, Milner JD, et al. J Allergy Clin Immunol. 2024 Jan; 153(1):230-242. Epub 2023 Sep 26.

See all...

Reference sequence information

RefSeq alternative splicing
See 4 reference mRNA sequence splice variants for the PLCG2 gene.
RefSeq protein product
See the reference protein sequence for 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (NP_002652.2).

More about the PLCG2 gene

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bis...
Also Known As: APLAID, FCAS3, PLC-IV, ...

Related information

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
Taxonomy sequences associated with Nucleotide record
Annotated Genomic
Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
BioSystems
BioSystems
CCDS
Link to Consensus CDS
Components (Core)
Links to Core components
Full text in PMC
Free full text articles in PMC
Functional Class
Functional class of the sequence domain architecture
Gene
Link to related Genes
OMIM
OMIM records associated with Nucleotide sequence
Probe
Related Probe entry
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed

LinkOut to external resources

Ensembl [Ensembl]
Ensembl
PLCgamma2 [Guide to Pharmacology]
PLCgamma2
Guide to Pharmacology
GenScript latest version of gene cDNA ORF Clone [GenScript latest version of g...]
GenScript latest version of gene cDNA ORF Clone
Order TALEN/CRISPR clone [GeneCopoeia Inc.]
Order TALEN/CRISPR clone
GeneCopoeia Inc.
Order qPCR primer [GeneCopoeia Inc.]
Order qPCR primer
GeneCopoeia Inc.
Order full-length cDNA clone [GeneCopoeia Inc.]
Order full-length cDNA clone
GeneCopoeia Inc.
UCSC Genome Browser [UCSC Genome Browser]
UCSC Genome Browser

Recent activity

Clear Turn Off Turn On

Homo sapiens apelin (APLN), mRNA
Homo sapiens apelin (APLN), mRNA
gi|47078297|ref|NM_017413.3|

Nucleotide

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

Nucleotide

Result Filters

Send to:

Homo sapiens phospholipase C gamma 2 (PLCG2), transcript variant 1, mRNA

Supplemental Content

Analyze this sequence

Articles about the PLCG2 gene

Reference sequence information

More about the PLCG2 gene

Related information

LinkOut to external resources

Recent activity