Homo sapiens elastase, neutrophil expressed (ELANE), mRNA

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Pick Primers
Design and test primers for this sequence using Primer-BLAST.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Elevated first-trimester neutrophil elastase and proteinase 3 increase the risk of gestational diabetes mellitus and adverse fetal outcomes. [Reprod Biol Endocrinol. 2024]
Elevated first-trimester neutrophil elastase and proteinase 3 increase the risk of gestational diabetes mellitus and adverse fetal outcomes.
Wang L, Zhou Z, Xu X, Li Y, Zhang R, Yu Z, Huang X, Zang S, Sun T. Reprod Biol Endocrinol. 2024 Jan 2; 22(1):2. Epub 2024 Jan 2.
Position-specific N- and O-glycosylation of the reactive center loop impacts neutrophil elastase-mediated proteolysis of corticosteroid-binding globulin. [J Biol Chem. 2024]
Position-specific N- and O-glycosylation of the reactive center loop impacts neutrophil elastase-mediated proteolysis of corticosteroid-binding globulin.
Chernykh A, Abrahams JL, Grant OC, Kambanis L, Sumer-Bayraktar Z, Ugonotti J, Kawahara R, Corcilius L, Payne RJ, Woods RJ, et al. J Biol Chem. 2024 Jan; 300(1):105519. Epub 2023 Nov 30.
Neutrophil Elastase Remodels Mammary Tumors to Facilitate Lung Metastasis. [Mol Cancer Ther. 2024]
Neutrophil Elastase Remodels Mammary Tumors to Facilitate Lung Metastasis.
Lulla AR, Akli S, Karakas C, Caruso JA, Warma LD, Fowlkes NW, Rao X, Wang J, Hunt KK, Watowich SS, et al. Mol Cancer Ther. 2024 Apr 2; 23(4):492-506.

RefSeq alternative splicing
See 5 reference mRNA sequence splice variants for the ELANE gene.
RefSeq protein product
See the reference protein sequence for neutrophil elastase preproprotein (NP_001963.1).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
Taxonomy sequences associated with Nucleotide record
Annotated Genomic
Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
BioSystems
BioSystems
CCDS
Link to Consensus CDS
Components (Core)
Links to Core components
Full text in PMC
Free full text articles in PMC
Functional Class
Functional class of the sequence domain architecture
Gene
Link to related Genes
OMIM
OMIM records associated with Nucleotide sequence
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed

Ensembl [Ensembl]
Ensembl
Ensembl [Ensembl]
Ensembl
elastase, neutrophil expressed [Guide to Pharmacology]
elastase, neutrophil expressed
Guide to Pharmacology
GenScript latest version of gene cDNA ORF Clone [GenScript latest version of g...]
GenScript latest version of gene cDNA ORF Clone
Order TALEN/CRISPR clone [GeneCopoeia Inc.]
Order TALEN/CRISPR clone
GeneCopoeia Inc.
Order qPCR primer [GeneCopoeia Inc.]
Order qPCR primer
GeneCopoeia Inc.
Order full-length cDNA clone [GeneCopoeia Inc.]
Order full-length cDNA clone
GeneCopoeia Inc.
UCSC Genome Browser [UCSC Genome Browser]
UCSC Genome Browser

Your browsing activity is empty.

Activity recording is turned off.

Nucleotide