Homo sapiens APC regulator of WNT signaling pathway (APC), transcript - Nucleotide

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β-catenin mediates growth defects induced by centrosome loss in a subset of APC mutant colorectal cancer independently of p53. [PLoS One. 2024]
β-catenin mediates growth defects induced by centrosome loss in a subset of APC mutant colorectal cancer independently of p53.
Bourmoum M, Radulovich N, Sharma A, Tkach JM, Tsao MS, Pelletier L. PLoS One. 2024; 19(2):e0295030. Epub 2024 Feb 7.
APC mutations disrupt β-catenin destruction complex condensates organized by Axin phase separation. [Cell Mol Life Sci. 2024]
APC mutations disrupt β-catenin destruction complex condensates organized by Axin phase separation.
Zhang D, Ni QQ, Wang SY, He WF, Hong ZX, Liu HY, Chen XH, Chen LJ, Han FY, Zhang LJ, et al. Cell Mol Life Sci. 2024 Jan 27; 81(1):57. Epub 2024 Jan 27.
BET protein-dependent E2F pathway activity confers bell-shaped type resistance to tankyrase inhibitors in APC-mutated colorectal cancer. [Cancer Lett. 2024]
BET protein-dependent E2F pathway activity confers bell-shaped type resistance to tankyrase inhibitors in APC-mutated colorectal cancer.
Morino S, Mashima T, Shirai F, Nagayama S, Katayama R, Seimiya H. Cancer Lett. 2024 Mar 1; 584:216632. Epub 2024 Jan 11.

RefSeq alternative splicing
See 35 reference mRNA sequence splice variants for the APC gene.
RefSeq protein product
See the reference protein sequence for adenomatous polyposis coli protein isoform e (NP_001341827.1).

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Protein sequence from Nucleotide coding region
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Nucleotide