Homo sapiens glucokinase (GCK), transcript variant 7, mRNA

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Characterizing glucokinase variant mechanisms using a multiplexed abundance assay. [Genome Biol. 2024]
Characterizing glucokinase variant mechanisms using a multiplexed abundance assay.
Gersing S, Schulze TK, Cagiada M, Stein A, Roth FP, Lindorff-Larsen K, Hartmann-Petersen R. Genome Biol. 2024 Apr 16; 25(1):98. Epub 2024 Apr 16.
Glucokinase Variant Proteins Are Resistant to Fasting-Induced Uridine Diphosphate Glucose-Dependent Degradation in Maturity-Onset Diabetes of the Young Type 2 Patients. [Int J Mol Sci. 2023]
Glucokinase Variant Proteins Are Resistant to Fasting-Induced Uridine Diphosphate Glucose-Dependent Degradation in Maturity-Onset Diabetes of the Young Type 2 Patients.
Cho J, Horikawa Y, Oiwa Y, Hosomichi K, Yabe D, Imai T. Int J Mol Sci. 2023 Oct 31; 24(21). Epub 2023 Oct 31.
Two novel GCK mutations in Chinese patients with maturity-onset diabetes of the young. [Endocrine. 2024]
Two novel GCK mutations in Chinese patients with maturity-onset diabetes of the young.
Wang T, Zhu M, Wang Y, Hu C, Fang C, Hu J. Endocrine. 2024 Jan; 83(1):92-98. Epub 2023 Oct 17.

RefSeq alternative splicing
See 9 reference mRNA sequence splice variants for the GCK gene.
RefSeq protein product
See the reference protein sequence for hexokinase-4 isoform 7 (NP_001341730.1).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
Taxonomy sequences associated with Nucleotide record
Annotated Genomic
Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
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BioSystems
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Functional Class
Functional class of the sequence domain architecture
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OMIM
OMIM records associated with Nucleotide sequence
PubMed (RefSeq)
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PubMed (Weighted)
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SNP
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Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and ...<br/>

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Nucleotide