Homo sapiens DNA ligase 4 (LIG4), transcript variant 7, mRNA

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The Contribution of DNA Ligase 4 Polymorphisms to Colorectal Cancer. [In Vivo. 2024]
The Contribution of DNA Ligase 4 Polymorphisms to Colorectal Cancer.
Deng Y, Ke TW, Yueh TC, Chin YT, Wang YC, Hung YC, Mong MC, Yang YC, Wu WT, Chang WS, et al. In Vivo. 2024 Jan-Feb; 38(1):127-133.
Deficiency of ligase IV leads to reduced NHEJ, accumulation of DNA damage, and can sensitize cells to cancer therapeutics. [Genomics. 2023]
Deficiency of ligase IV leads to reduced NHEJ, accumulation of DNA damage, and can sensitize cells to cancer therapeutics.
Kumari N, Antil H, Kumari S, Raghavan SC. Genomics. 2023 Nov; 115(6):110731. Epub 2023 Oct 21.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4-Associated Factors, Cellular Functions, and Protein Substrates. [Mol Cell Proteomics. 2023]
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4-Associated Factors, Cellular Functions, and Protein Substrates.
Raisch J, Dubois ML, Groleau M, Lévesque D, Burger T, Jurkovic CM, Brailly R, Marbach G, McKenna A, Barrette C, et al. Mol Cell Proteomics. 2023 Oct; 22(10):100644. Epub 2023 Sep 7.

RefSeq alternative splicing
See 12 reference mRNA sequence splice variants for the LIG4 gene.
RefSeq protein product
See the reference protein sequence for DNA ligase 4 isoform 1 (NP_001339529.1).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
Taxonomy sequences associated with Nucleotide record
Annotated Genomic
Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
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BioSystems
CCDS
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Components (Core)
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Functional Class
Functional class of the sequence domain architecture
Gene
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OMIM
OMIM records associated with Nucleotide sequence
PubMed (RefSeq)
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PubMed (Weighted)
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Nucleotide