Homo sapiens checkpoint kinase 2 (CHEK2), transcript variant 5, mRNA

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LINC00982-encoded protein PRDM16-DT regulates CHEK2 splicing to suppress colorectal cancer metastasis and chemoresistance. [Theranostics. 2024]
LINC00982-encoded protein PRDM16-DT regulates CHEK2 splicing to suppress colorectal cancer metastasis and chemoresistance.
Hu HF, Han L, Fu JY, He X, Tan JF, Chen QP, Han JR, He QY. Theranostics. 2024; 14(8):3317-3338. Epub 2024 May 27.
A deep intronic recurrent CHEK2 variant c.1009-118_1009-87delinsC affects pre-mRNA splicing and contributes to hereditary breast cancer predisposition. [Breast. 2024]
A deep intronic recurrent CHEK2 variant c.1009-118_1009-87delinsC affects pre-mRNA splicing and contributes to hereditary breast cancer predisposition.
Zemankova P, Cerna M, Horackova K, Ernst C, Soukupova J, Borecka M, Blümcke B, Cerna L, Cerna M, Curtisova V, et al. Breast. 2024 Jun; 75:103721. Epub 2024 Mar 25.
Germline CHEK2 mutations in patients with myeloid neoplasms. [Leukemia. 2024]
Germline CHEK2 mutations in patients with myeloid neoplasms.
Freiman L, Larcher L, Tueur G, Vasquez N, Da Costa M, Duchmann M, Raffoux E, Adès L, Fenaux P, Soulier J, et al. Leukemia. 2024 Apr; 38(4):908-911. Epub 2024 Feb 20.

RefSeq alternative splicing
See 35 reference mRNA sequence splice variants for the CHEK2 gene.
RefSeq protein product
See the reference protein sequence for serine/threonine-protein kinase Chk2 isoform e (NP_001336885.1).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
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Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
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OMIM
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Links from autonomous proteins to species level organisms for Protein (Select 2445955235)
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Nucleotide