Homo sapiens mitochondrial trans-2-enoyl-CoA reductase (MECR), transcr - Nucleotide

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Recessive MECR pathogenic variants cause an LHON-like optic neuropathy. [J Med Genet. 2023]
Recessive MECR pathogenic variants cause an LHON-like optic neuropathy.
Fiorini C, Degiorgi A, Cascavilla ML, Tropeano CV, La Morgia C, Battista M, Ormanbekova D, Palombo F, Carbonelli M, Bandello F, et al. J Med Genet. 2023 Dec 21; 61(1):93-101. Epub 2023 Dec 21.
Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6. [Science. 2023]
Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6.
Dietz L, Ellison CJ, Riechmann C, Cassidy CK, Felfoldi FD, Pinto-Fernández A, Kessler BM, Elliott PR. Science. 2023 Mar 17; 379(6637):1112-1117. Epub 2023 Feb 9.
Alternative splicing liberates a cryptic cytoplasmic isoform of mitochondrial MECR that antagonizes influenza virus. [PLoS Biol. 2022]
Alternative splicing liberates a cryptic cytoplasmic isoform of mitochondrial MECR that antagonizes influenza virus.
Baker SF, Meistermann H, Tzouros M, Baker A, Golling S, Polster JS, Ledwith MP, Gitter A, Augustin A, Javanbakht H, et al. PLoS Biol. 2022 Dec; 20(12):e3001934. Epub 2022 Dec 21.

RefSeq alternative splicing
See 23 reference mRNA sequence splice variants for the MECR gene.

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Nucleotide