Homo sapiens Janus kinase 1 (JAK1), transcript variant 6, mRNA

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Individuals with JAK1 variants are affected by syndromic features encompassing autoimmunity, atopy, colitis, and dermatitis. [J Exp Med. 2024]
Individuals with JAK1 variants are affected by syndromic features encompassing autoimmunity, atopy, colitis, and dermatitis.
Horesh ME, Martin-Fernandez M, Gruber C, Buta S, Le Voyer T, Puzenat E, Lesmana H, Wu Y, Richardson A, Stein D, et al. J Exp Med. 2024 Jun 3; 221(6). Epub 2024 Apr 2.
CD146(+)CAFs promote progression of endometrial cancer by inducing angiogenesis and vasculogenic mimicry via IL-10/JAK1/STAT3 pathway. [Cell Commun Signal. 2024]
CD146(+)CAFs promote progression of endometrial cancer by inducing angiogenesis and vasculogenic mimicry via IL-10/JAK1/STAT3 pathway.
Yu Z, Zhang Q, Wei S, Zhang Y, Zhou T, Zhang Q, Shi R, Zinovkin D, Pranjol ZI, Zhang J, et al. Cell Commun Signal. 2024 Mar 8; 22(1):170. Epub 2024 Mar 8.
Single-cell deconvolution algorithms analysis unveils autocrine IL11-mediated resistance to docetaxel in prostate cancer via activation of the JAK1/STAT4 pathway. [J Exp Clin Cancer Res. 2024]
Single-cell deconvolution algorithms analysis unveils autocrine IL11-mediated resistance to docetaxel in prostate cancer via activation of the JAK1/STAT4 pathway.
Cheng B, Li L, Luo T, Wang Q, Luo Y, Bai S, Li K, Lai Y, Huang H. J Exp Clin Cancer Res. 2024 Mar 1; 43(1):67. Epub 2024 Mar 1.

RefSeq alternative splicing
See 15 reference mRNA sequence splice variants for the JAK1 gene.
RefSeq protein product
See the reference protein sequence for tyrosine-protein kinase JAK1 isoform 1 (NP_001308784.1).

Protein
Protein sequence from Nucleotide coding region
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Nucleotide