Homo sapiens SP140 nuclear body protein (SP140), transcript variant 4, - Nucleotide

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Pick Primers
Design and test primers for this sequence using Primer-BLAST.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

SP140 inhibits STAT1 signaling, induces IFN-γ in tumor-associated macrophages, and is a predictive biomarker of immunotherapy response. [J Immunother Cancer. 2022]
SP140 inhibits STAT1 signaling, induces IFN-γ in tumor-associated macrophages, and is a predictive biomarker of immunotherapy response.
Tanagala KKK, Morin-Baxter J, Carvajal R, Cheema M, Dubey S, Nakagawa H, Yoon A, Cheng YL, Taylor A, Nickerson J, et al. J Immunother Cancer. 2022 Dec; 10(12).
Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease. [Cell Host Microbe. 2022]
Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease.
Fraschilla I, Amatullah H, Rahman RU, Jeffrey KL. Cell Host Microbe. 2022 Oct 12; 30(10):1370-1381.e5. Epub 2022 Sep 20.
Epigenetic reader SP140 loss of function drives Crohn's disease due to uncontrolled macrophage topoisomerases. [Cell. 2022]
Epigenetic reader SP140 loss of function drives Crohn's disease due to uncontrolled macrophage topoisomerases.
Amatullah H, Fraschilla I, Digumarthi S, Huang J, Adiliaghdam F, Bonilla G, Wong LP, Rivard ME, Beauchamp C, Mercier V, et al. Cell. 2022 Aug 18; 185(17):3232-3247.e18. Epub 2022 Aug 10.

RefSeq alternative splicing
See 71 reference mRNA sequence splice variants for the SP140 gene.
RefSeq protein product
See the reference protein sequence for nuclear body protein SP140 isoform 4 (NP_001265381.1).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
Taxonomy sequences associated with Nucleotide record
Annotated Genomic
Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
BioSystems
BioSystems
CCDS
Link to Consensus CDS
Components (Core)
Links to Core components
Full text in PMC
Free full text articles in PMC
Functional Class
Functional class of the sequence domain architecture
Gene
Link to related Genes
OMIM
OMIM records associated with Nucleotide sequence
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed

Ensembl [Ensembl]
Ensembl
GenScript latest version of gene cDNA ORF Clone [GenScript latest version of g...]
GenScript latest version of gene cDNA ORF Clone
Order TALEN/CRISPR clone [GeneCopoeia Inc.]
Order TALEN/CRISPR clone
GeneCopoeia Inc.
Order qPCR primer [GeneCopoeia Inc.]
Order qPCR primer
GeneCopoeia Inc.
Order full-length cDNA clone [GeneCopoeia Inc.]
Order full-length cDNA clone
GeneCopoeia Inc.
UCSC Genome Browser [UCSC Genome Browser]
UCSC Genome Browser

Homo sapiens ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 (ACAP1), m...
Homo sapiens ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 (ACAP1), mRNA
gi|1519241637|ref|NM_014716.4|

Nucleotide
tectonic-1 isoform X16 [Homo sapiens]
tectonic-1 isoform X16 [Homo sapiens]
gi|578824223|ref|XP_006719658.1|

Protein
tectonic-1 isoform X18 [Homo sapiens]
tectonic-1 isoform X18 [Homo sapiens]
gi|2462534386|ref|XP_054229201.1|

Protein
Homo sapiens transmembrane protein 229B (TMEM229B), transcript variant 8, mRNA
Homo sapiens transmembrane protein 229B (TMEM229B), transcript variant 8, mRNA
gi|1677501931|ref|NM_001348548.2|

Nucleotide

Your browsing activity is empty.

Activity recording is turned off.

Nucleotide