DEC1 represses cardiomyocyte hypertrophy by recruiting PRP19 as an E3 ligase to promote ubiquitination-proteasome-mediated degradation of GATA4.
Cheng L, Xu C, Chen Y, Li J, Wang J, Xiao J, Ma M, Feng X, Wei X, Fang J. J Mol Cell Cardiol. 2022 Aug; 169:96-110. Epub 2022 May 31.