Homo sapiens thyroid peroxidase (TPO), transcript variant 6, mRNA

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Articles about the TPO gene

Is There a Link between Thyroid Peroxidase Gene Promoter Polymorphisms and Autoimmune Thyroiditis in the Polish Population? [Int J Mol Sci. 2024]
Is There a Link between Thyroid Peroxidase Gene Promoter Polymorphisms and Autoimmune Thyroiditis in the Polish Population?
Lacka K, Maciejewski A, Jarecki P, Herman W, Lacki JK, Żaba R, Kowalczyk MJ. Int J Mol Sci. 2024 Mar 14; 25(6). Epub 2024 Mar 14.
Disulfide Bonds of Thyroid Peroxidase Are Critical Elements for Subcellular Localization, Proteasome-Dependent Degradation, and Enzyme Activity. [Thyroid. 2024]
Disulfide Bonds of Thyroid Peroxidase Are Critical Elements for Subcellular Localization, Proteasome-Dependent Degradation, and Enzyme Activity.
Iwasaki H, Suwanai H, Yakou F, Sakai H, Ishii K, Hara N, Buckle AM, Kanekura K, Miyagi T, Narumi S, et al. Thyroid. 2024 May; 34(5):659-667. Epub 2024 Apr 11.
Homozygous Mutations in Thyroid Peroxidase (TPO) in Hypothyroidism with Intellectual Disability, Developmental Delay, and Hearing and Ocular Anomalies in Two Families: Severe Manifestation of Untreated TPO-deficiency Poses a Diagnostic Dilemma. [Yale J Biol Med. 2023]
Homozygous Mutations in Thyroid Peroxidase (TPO) in Hypothyroidism with Intellectual Disability, Developmental Delay, and Hearing and Ocular Anomalies in Two Families: Severe Manifestation of Untreated TPO-deficiency Poses a Diagnostic Dilemma.
Naqvi SF, Yıldız-Bölükbaşı E, Afzal M, Nalbant G, Mumtaz S, Tolun A, Malik S. Yale J Biol Med. 2023 Sep; 96(3):347-365. Epub 2023 Sep 29.

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Reference sequence information

RefSeq protein product
See the reference protein sequence for thyroid peroxidase isoform a precursor (NP_001193673.1).

More about the TPO gene

This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. T...
Also Known As: MSA, TDH2A, TPX

Related information

Protein
Protein sequence from Nucleotide coding region
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PubMed articles cited by Nucleotide sequence record
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Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
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BioSystems
CCDS
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Components (Core)
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Full text in PMC
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Functional Class
Functional class of the sequence domain architecture
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PubMed (RefSeq)
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Dryad Digital Repository [Dryad Digital Repository]
Dryad Digital Repository
Ensembl [Ensembl]
Ensembl
Ensembl [Ensembl]
Ensembl
thyroid peroxidase [Guide to Pharmacology]
thyroid peroxidase
Guide to Pharmacology
GenScript latest version of gene cDNA ORF Clone [GenScript latest version of g...]
GenScript latest version of gene cDNA ORF Clone
Order TALEN/CRISPR clone [GeneCopoeia Inc.]
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GeneCopoeia Inc.
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GeneCopoeia Inc.
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UCSC Genome Browser

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Articles about the TPO gene

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