Homo sapiens interferon regulatory factor 3 (IRF3), transcript variant - Nucleotide

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Mammalian reovirus µ1 protein attenuates RIG-I and MDA5-mediated signaling transduction by blocking IRF3 phosphorylation and nuclear translocation. [Mol Immunol. 2024]
Mammalian reovirus µ1 protein attenuates RIG-I and MDA5-mediated signaling transduction by blocking IRF3 phosphorylation and nuclear translocation.
Wu B, Li D, Bai H, Mo R, Li H, Xie J, Zhang X, Yang Y, Li H, Idris A, et al. Mol Immunol. 2024 Jun; 170:131-143. Epub 2024 Apr 24.
Deubiquitinase USP4 suppresses antitumor immunity by inhibiting IRF3 activation and tumor cell-intrinsic interferon response in colorectal cancer. [Cancer Lett. 2024]
Deubiquitinase USP4 suppresses antitumor immunity by inhibiting IRF3 activation and tumor cell-intrinsic interferon response in colorectal cancer.
Zhou Y, Li H, Zhang Y, Zhao E, Huang C, Pan X, Shu F, Liu Z, Tang N, Li F, et al. Cancer Lett. 2024 May 1; 589:216836. Epub 2024 Mar 30.
The African Swine Fever Virus Virulence Determinant DP96R Suppresses Type I IFN Production Targeting IRF3. [Int J Mol Sci. 2024]
The African Swine Fever Virus Virulence Determinant DP96R Suppresses Type I IFN Production Targeting IRF3.
Dodantenna N, Cha JW, Chathuranga K, Chathuranga WAG, Weerawardhana A, Ranathunga L, Kim Y, Jheong W, Lee JS. Int J Mol Sci. 2024 Feb 8; 25(4). Epub 2024 Feb 8.

RefSeq alternative splicing
See 30 reference mRNA sequence splice variants for the IRF3 gene.
RefSeq protein product
See the reference protein sequence for interferon regulatory factor 3 isoform 6 (NP_001184056.1).

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Protein sequence from Nucleotide coding region
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Homologene neighbors for GEO Profiles (Select 84134791) (0)
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Homologene neighbors for GEO Profiles (Select 66804425) (0)
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Profile neighbors for GEO Profiles (Select 66784240) (199)
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Profile neighbors for GEO Profiles (Select 84138414) (199)
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Profile neighbors for GEO Profiles (Select 66798241) (199)
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Nucleotide