Homo sapiens ADAM metallopeptidase domain 10 (ADAM10), transcript vari - Nucleotide

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Ectodomain shedding of PLA2R1 is mediated by the metalloproteases ADAM10 and ADAM17. [J Biol Chem. 2024]
Ectodomain shedding of PLA2R1 is mediated by the metalloproteases ADAM10 and ADAM17.
Dolla G, Nicolas S, Dos Santos LR, Bourgeois A, Pardossi-Piquard R, Bihl F, Zaghrini C, Justino J, Payré C, Mansuelle P, et al. J Biol Chem. 2024 Jul; 300(7):107480. Epub 2024 Jun 17.
Downregulation of the metalloproteinases ADAM10 or ADAM17 promotes osteoclast differentiation. [Cell Commun Signal. 2024]
Downregulation of the metalloproteinases ADAM10 or ADAM17 promotes osteoclast differentiation.
Babendreyer A, Kieselhorst J, Rinkens C, Lyashenko AM, Düsterhöft S, Jahr H, Craveiro RB, Wolf M, Ludwig A. Cell Commun Signal. 2024 Jun 11; 22(1):322. Epub 2024 Jun 11.
ADAM10 as a major activator of reactive oxygen species production and klotho shedding in podocytes under diabetic conditions. [Biochem Pharmacol. 2024]
ADAM10 as a major activator of reactive oxygen species production and klotho shedding in podocytes under diabetic conditions.
Piwkowska A, Rachubik P, Typiak M, Kulesza T, Audzeyenka I, Saleem MA, Gruba N, Wysocka M, Lesner A, Rogacka D. Biochem Pharmacol. 2024 Jul; 225:116328. Epub 2024 May 28.

RefSeq alternative splicing
See the other reference mRNA sequence splice variant for the ADAM10 gene (NM_001320570.2).
RefSeq protein product
See the reference protein sequence for disintegrin and metalloproteinase domain-containing protein 10 isoform 1 preproprotein (NP_001101.1).

Protein
Protein sequence from Nucleotide coding region
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Ensembl [Ensembl]
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ADAM10 [Guide to Pharmacology]
ADAM10
Guide to Pharmacology
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Nucleotide