Homo sapiens sodium voltage-gated channel alpha subunit 2 (SCN2A), tra - Nucleotide

Run BLAST
Find regions of similarity between this sequence and other sequences using BLAST.
Pick Primers
Design and test primers for this sequence using Primer-BLAST.
Show in Genome Data Viewer
Opens the Genome Data Viewer, NCBI's genome browser, at the genomic location at which this sequence is annotated. View this sequence in the context of other features annotated at the same location and browse to other genome regions.

Pathogenic gating pore current conducted by autism-related mutations in the Na(V)1.2 brain sodium channel. [Proc Natl Acad Sci U S A. 2024]
Pathogenic gating pore current conducted by autism-related mutations in the Na(V)1.2 brain sodium channel.
Eltokhi A, Lundstrom BN, Li J, Zweifel LS, Catterall WA, Gamal El-Din TM. Proc Natl Acad Sci U S A. 2024 Apr 9; 121(15):e2317769121. Epub 2024 Apr 2.
Distinctive In Vitro Phenotypes in iPSC-Derived Neurons From Patients With Gain- and Loss-of-Function SCN2A Developmental and Epileptic Encephalopathy. [J Neurosci. 2024]
Distinctive In Vitro Phenotypes in iPSC-Derived Neurons From Patients With Gain- and Loss-of-Function SCN2A Developmental and Epileptic Encephalopathy.
Mao M, Mattei C, Rollo B, Byars S, Cuddy C, Berecki G, Heighway J, Pachernegg S, Menheniott T, Apted D, et al. J Neurosci. 2024 Feb 21; 44(8). Epub 2024 Feb 21.
Exome sequencing of ATP1A3-negative cases of alternating hemiplegia of childhood reveals SCN2A as a novel causative gene. [Eur J Hum Genet. 2024]
Exome sequencing of ATP1A3-negative cases of alternating hemiplegia of childhood reveals SCN2A as a novel causative gene.
Panagiotakaki E, Tiziano FD, Mikati MA, Vijfhuizen LS, Nicole S, Lesca G, Abiusi E, Novelli A, Di Pietro L, I.B.AHC Consortium, et al. Eur J Hum Genet. 2024 Feb; 32(2):224-231. Epub 2023 Dec 14.

RefSeq alternative splicing
See 5 reference mRNA sequence splice variants for the SCN2A gene.
RefSeq protein product
See the reference protein sequence for sodium channel protein type 2 subunit alpha isoform 1 (NP_001035232.1).

Protein
Protein sequence from Nucleotide coding region
PubMed
PubMed articles cited by Nucleotide sequence record
Taxonomy
Taxonomy sequences associated with Nucleotide record
Annotated Genomic
Genomic sequence records that have the current RNA records as annotated features marking the exons of genes.
BioSystems
BioSystems
CCDS
Link to Consensus CDS
Components (Core)
Links to Core components
Full text in PMC
Free full text articles in PMC
Functional Class
Functional class of the sequence domain architecture
Gene
Link to related Genes
OMIM
OMIM records associated with Nucleotide sequence
PubMed (RefSeq)
Link to RefSeq PubMed articles
PubMed (Weighted)
Links to pubmed

Ensembl [Ensembl]
Ensembl
Nav1.2 [Guide to Pharmacology]
Nav1.2
Guide to Pharmacology
GenScript latest version of gene cDNA ORF Clone [GenScript latest version of g...]
GenScript latest version of gene cDNA ORF Clone
Order TALEN/CRISPR clone [GeneCopoeia Inc.]
Order TALEN/CRISPR clone
GeneCopoeia Inc.
Order qPCR primer [GeneCopoeia Inc.]
Order qPCR primer
GeneCopoeia Inc.
UCSC Genome Browser [UCSC Genome Browser]
UCSC Genome Browser

Your browsing activity is empty.

Activity recording is turned off.

Nucleotide